behaviors

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2026-04-16 11:02:50 +02:00
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@@ -11,37 +11,51 @@ Qui comprendiamo:
---
**Simplified behaviors**:
**Simplified verifiable behaviors**:
— ms:
- Resting at -70 mV: Leak channels + pumps (keep at resting)
-- ?
- VDB Depolarization : ~1-2 ms: Na⁺ enters (some VGSCs open)
- Opened VGSC remain closed for a refractory period
Spike if depolarized above threshold: to -50 mV
-- Here the threshold is based only on the integration of Na+
-- The threshold is tuned during the spiketrain. Low threshold at rest, to increase sensitivity, threshold increase during spike to increase discrimination
-- increase SpikeTrainTraces (fast at spike)
-- increase Ca2+ traces
- Opened VGSC and then remain closed for a refractory period
- Spike if depolarized above threshold: to -50 mV
- Ca2+ enter
- Repolarization to -70 mV: ~1-2 ms: K⁺ exits (VG K⁺ channels open) ← NOT pumps!
-- fast pump which decreases Na+, we do not model K+
- After-hyperpolarization: ~5-20 ms: K⁺ channels still open
-- must figure out how to deal with deoplarization
-- decrease SpikeTraintraces slow, only if away from spiketrain this is empty
— seconds:
— secs:
- Return to exact -70 mV: ~100-1000 ms: Na⁺/K⁺ pumps restore gradients
-- slow pump
- Ca2+ accumulation: SpikeTrainTraces
-- ?
- Ca2+ accumulation
— mins:
- VGSC modulation
---
**G expression**:
— ms:
- Here the threshold is based only on the integration of Na+
- The threshold is tuned during the spiketrain. Low threshold at rest, to increase sensitivity, threshold increase during spike to increase discrimination
- increase SpikeTrainTraces (fast at spike)
- increase Ca2+ traces
- fast pump which decreases Na+, we do not model K+
- must figure out how to deal with deoplarization
- decrease SpikeTraintraces slow, only if away from spiketrain this is empty
— secs:
- SpikeTrainTraces
— mins:
---
**Tubs:**
- **VDB**: dendrites deliver current