cambio label aggiunta organi

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2026-04-14 15:24:01 +02:00
parent 4a0ec7fbe9
commit 549ba3cee3
6 changed files with 51 additions and 52 deletions
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Qui comprendiamo: Qui comprendiamo:
- BEH-AXO: Axon - AXON: Axon
- BEH-PRE: Presynapse - PRESYNAPSE: Presynapse
- BEH-VCGG: Voltage-Controlled Gated Channels - VGCC-PRE: Voltage-Controlled Gated Channels
## BEH-AXO: Container ## AXON: Container
The axon does not contain specific behavior. We might add balancing of ATP within PRE later. Here we comprehend it as a “cable” transporting the AP from SOMA to Presynapse. It expands BEH-PRE which: The axon does not contain specific behavior. We might add balancing of ATP within PRE later. Here we comprehend it as a “cable” transporting the AP from SOMA to Presynapse. It expands PRESYNAPSE which:
- can be developed by DEV-PRE - can be developed by DEV-PRE
- the associations between BEH-PRE, BEH-POST e BEH-SYN is performed by the module that instantiate the Neurons and the Atrocytes, for example BEH-EXH or BEH-INH from winnertakeall. - the associations between PRESYNAPSE, BEH-POST e BEH-SYN is performed by the module that instantiate the Neurons and the Atrocytes, for example BEH-EXH or BEH-INH from winnertakeall.
```Gen ```Gen
container: BEH-AXO container: AXON
expansion: BEH-PRE ( full: 50x, active: 0x, empty: 10x ) expansion: PRESYNAPSE ( full: 50x, active: 0x, empty: 10x )
# managed_by: BEH-EXH or BEH-INH from winnertakeall # managed_by: BEH-EXH or BEH-INH from winnertakeall
# developed_by: DEV-AXO-BEH-PRE-TUB from DEV-N # developed_by: DEV-AXO-PRESYNAPSE-TUB from DEV-N
``` ```
## BEH-PRE: Container ## PRESYNAPSE: Container
**Discursive description**: **Discursive description**:
@@ -177,10 +177,9 @@ The simplification impies that:
--- ---
```Gen ```Gen
container: BEH-PRE container: PRESYNAPSE
expansion: BEH-PRE-VGCC ( full: 10x, active: 5x, empty: 2x ) expansion: VGCC-PRE ( full: 10x, active: 5x, empty: 2x )
# tuned_by: TUN-PRE-VGCC from TUN.N
tub_local: tub_local:
- Ca2+ ( full: 60x, active: 30x, empty: 0x ) - Ca2+ ( full: 60x, active: 30x, empty: 0x )
@@ -204,7 +203,7 @@ container: BEH-PRE
``` ```
### ms: behaviors PRE ### ms: behaviors
#### AP-RRPConcentration: Context #### AP-RRPConcentration: Context
@@ -216,7 +215,7 @@ Questo poi per permettere la diversa contestualizzazione degli episodi di NTrele
```Gen ```Gen
context: AP-RRPConcentration context: AP-RRPConcentration
contained_by: BEH-PRE contained_by: PRESYNAPSE
in_context: AP in_context: AP
rf: ( active: 60x ) rf: ( active: 60x )
@@ -234,7 +233,7 @@ Qui controlliamo la concentrazione nel contesto di un AP.
```Gen ```Gen
context: AP-Ca2+Concentration context: AP-Ca2+Concentration
contained_by: BEH-PRE contained_by: PRESYNAPSE
in_context: AP in_context: AP
rf: ( active: 60x ) rf: ( active: 60x )
@@ -260,7 +259,7 @@ NT empty
```Gen ```Gen
episode: NTreleaseMaximum episode: NTreleaseMaximum
contained_by: BEH-PRE contained_by: PRESYNAPSE
in_context: (Ca2+Full AND RRPFull) in_context: (Ca2+Full AND RRPFull)
rf: ( active: 3x ) # Maximum rf: ( active: 3x ) # Maximum
@@ -276,7 +275,7 @@ Solo in questo caso NT modera! NT NOT empty
```Gen ```Gen
episode: NTreleaseHigh episode: NTreleaseHigh
contained_by: BEH-PRE contained_by: PRESYNAPSE
in_context: (Ca2+Full AND RRPFull) in_context: (Ca2+Full AND RRPFull)
rf: ( active: 6x ) # High rf: ( active: 6x ) # High
@@ -292,7 +291,7 @@ In tutti i casi di NT
```Gen ```Gen
episode: NTreleaseMediumness episode: NTreleaseMediumness
contained_by: BEH-PRE contained_by: PRESYNAPSE
in_context: (Ca2+Full AND RRPMediumness) OR (Ca2+Mediumness AND RRPFull) in_context: (Ca2+Full AND RRPMediumness) OR (Ca2+Mediumness AND RRPFull)
rf: ( active: 9x ) # Mediumness rf: ( active: 9x ) # Mediumness
@@ -308,7 +307,7 @@ In tutti i casi di NT
```Gen ```Gen
episode: NTreleaseLow episode: NTreleaseLow
contained_by: BEH-PRE contained_by: PRESYNAPSE
in_context: (Ca2+Mediumness AND RRPMediumness) in_context: (Ca2+Mediumness AND RRPMediumness)
rf: ( active: 12x ) # Low rf: ( active: 12x ) # Low
@@ -334,7 +333,7 @@ Abbiamo il caso di clearance nel contesto di un AP e non nel contesto di AP, per
```Gen ```Gen
episode: AP-CaClearanceHigh episode: AP-CaClearanceHigh
contained_by: BEH-PRE contained_by: PRESYNAPSE
in_context: Ca2+Full in_context: Ca2+Full
rf: ( active: 3x ) # High rf: ( active: 3x ) # High
@@ -348,7 +347,7 @@ episode: AP-CaClearanceHigh
```Gen ```Gen
episode: AP-CaClearanceMediumness episode: AP-CaClearanceMediumness
contained_by: BEH-PRE contained_by: PRESYNAPSE
in_context: Ca2+Mediumness in_context: Ca2+Mediumness
rf: ( active: 6x ) # mediumness rf: ( active: 6x ) # mediumness
@@ -362,7 +361,7 @@ episode: AP-CaClearanceMediumness
```Gen ```Gen
episode: NotAP-CaClearance episode: NotAP-CaClearance
contained_by: BEH-PRE contained_by: PRESYNAPSE
in_context: NOT AP in_context: NOT AP
rf: ( active: 24x ) # Low rf: ( active: 24x ) # Low
@@ -384,7 +383,7 @@ The result is that Tr_Ca encodes not the instantaneous calcium level but the rec
```Gen ```Gen
episode: CaTracesAccumulationFast episode: CaTracesAccumulationFast
contained_by: BEH-PRE contained_by: PRESYNAPSE
in_context: Ca2+Full in_context: Ca2+Full
rf: ( active: 12x ) # fast rf: ( active: 12x ) # fast
@@ -398,7 +397,7 @@ episode: CaTracesAccumulationFast
```Gen ```Gen
episode: CaTracesAccumulationSlow episode: CaTracesAccumulationSlow
contained_by: BEH-PRE contained_by: PRESYNAPSE
in_context: Ca2+Full in_context: Ca2+Full
rf: ( active: 24x ) # Slow rf: ( active: 24x ) # Slow
@@ -408,7 +407,7 @@ episode: CaTracesAccumulationSlow
trace: None trace: None
``` ```
### sec: behaviors PRE ### sec: behaviors
#### CheckConditionsPreSec: Context #### CheckConditionsPreSec: Context
@@ -416,7 +415,7 @@ Contestualizziamo in maniera Fixed ogni mezzo secondo?
```Gen ```Gen
context: CheckConditionsPreSec context: CheckConditionsPreSec
contained_by: BEH-PRE contained_by: PRESYNAPSE
in_context: Fixed in_context: Fixed
rf: ( active: 600x ) rf: ( active: 600x )
@@ -431,7 +430,7 @@ context: CheckConditionsPreSec
out_context: eCBNotEmpty out_context: eCBNotEmpty
``` ```
#### eCB clearance #### eCB clearance: Episode
eCB dipende da POST. Tende a modulare l'entrata di Ca2+ degli VGCC. eCB dipende da POST. Tende a modulare l'entrata di Ca2+ degli VGCC.
@@ -439,7 +438,7 @@ Qui non facciamo un flush di eCB, riduciamo ogni mezzo secondo (context) di un R
```Gen ```Gen
episode: eCBClearance episode: eCBClearance
contained_by: BEH-PRE contained_by: PRESYNAPSE
in_context: eCBNotEmpty in_context: eCBNotEmpty
rf: ( active: 24x ) # Slow rf: ( active: 24x ) # Slow
@@ -449,13 +448,13 @@ episode: eCBClearance
trace: None trace: None
``` ```
#### CaTraces clearance #### CaTraces clearance: Episode
Qui non facciamo un flush di Catrace, riduciamo ogni mezzo secondo (context) di un RF di questo episodio. Qui non facciamo un flush di Catrace, riduciamo ogni mezzo secondo (context) di un RF di questo episodio.
```Gen ```Gen
episode: CaTracesClearance episode: CaTracesClearance
contained_by: BEH-PRE contained_by: PRESYNAPSE
in_context: CaTracesNotEmpty in_context: CaTracesNotEmpty
rf: ( active: 24x ) # Slow rf: ( active: 24x ) # Slow
@@ -477,7 +476,7 @@ Rate: 0.00 0.25
```Gen ```Gen
episode: RPShuttleSlow episode: RPShuttleSlow
contained_by: BEH-PRE contained_by: PRESYNAPSE
in_context: RPShuttle in_context: RPShuttle
rf: ( active: 48x ) # Slow rf: ( active: 48x ) # Slow
@@ -495,7 +494,7 @@ Rate: 0.50 0.97
```Gen ```Gen
episode: RPShuttleModerate episode: RPShuttleModerate
contained_by: BEH-PRE contained_by: PRESYNAPSE
in_context: RPShuttle in_context: RPShuttle
rf: ( active: 24x ) # Slow rf: ( active: 24x ) # Slow
@@ -516,7 +515,7 @@ Rate: 1.25 1.94
```Gen ```Gen
episode: RPShuttleFast episode: RPShuttleFast
contained_by: BEH-PRE contained_by: PRESYNAPSE
in_context: RPShuttle in_context: RPShuttle
rf: ( active: 12x ) # Fast rf: ( active: 12x ) # Fast
@@ -536,7 +535,7 @@ Rate: 2.50 5.00
```Gen ```Gen
episode: RPShuttleMaximal episode: RPShuttleMaximal
contained_by: BEH-PRE contained_by: PRESYNAPSE
in_context: RPShuttle in_context: RPShuttle
rf: ( active: 6x ) # Maximal rf: ( active: 6x ) # Maximal
@@ -546,7 +545,7 @@ episode: RPShuttleMaximal
trace: None trace: None
``` ```
### min: behaviors PRE ### min: behaviors
#### Refill RP from Glutamine #### Refill RP from Glutamine
@@ -578,19 +577,19 @@ Gln — depletes over bursts, refilled by glucose (slowest, astrocyte-depend
Each tier buys time for the one below it to respond. When all three are depleted simultaneously — which only happens under prolonged high-frequency firing with insufficient glucose — the synapse has no remaining buffer and goes silent until the minutes loop restores the Glutamine_pool. Each tier buys time for the one below it to respond. When all three are depleted simultaneously — which only happens under prolonged high-frequency firing with insufficient glucose — the synapse has no remaining buffer and goes silent until the minutes loop restores the Glutamine_pool.
#### TUN-PRE-VGCC: Tuner #### VGCC-PRE-TUN: Tuner
```Gen ```Gen
Tuner: TUN-PRE-VGCC tuner: VGCC-PRE-TUN
contained_by: BEH-PRE contained_by: PRESYNAPSE
tunes: BEH-PRE/expansion/BEH-PRE-VCGG tunes: PRESYNAPSE/expansion/PRESYNAPSE-VCGG
tub_modulation: # in TUN agiamo su POS/ACT tub_modulation: # in TUN agiamo su POS/ACT
- posMod ( fullness: None, active: BEH-PRE-VCGG/fullness, empty: 0x) # riferimento a possible di BEH-PRE-VCGG - posMod ( fullness: None, active: PRESYNAPSE-VCGG/fullness, empty: 0x) # riferimento a possible di PRESYNAPSE-VCGG
- actMod ( fullness: None, active: BEH-PRE-VCGG/active, empty: BEH-PRE-VCGG/emptiness) # riferimento a active di BEH-PRE-VCGG - actMod ( fullness: None, active: PRESYNAPSE-VCGG/active, empty: PRESYNAPSE-VCGG/emptiness) # riferimento a active di PRESYNAPSE-VCGG
# qui stiamo modulando possible e actual di BEH-PRE-VCGG associandoli # qui stiamo modulando possible e actual di PRESYNAPSE-VCGG associandoli
# a posMod e actMod. Non serve associare una fullness perche' # a posMod e actMod. Non serve associare una fullness perche'
# la modulazione e' una pompa fra posMod e actMod e controlliamo # la modulazione e' una pompa fra posMod e actMod e controlliamo
# solo empty # solo empty
@@ -607,7 +606,7 @@ Tuner: TUN-PRE-VGCC
```Gen ```Gen
context: Check context: Check
contained_by: TUN-PRE-VGCC contained_by: VGCC-PRE-TUN
in_context: TunPossible in_context: TunPossible
rf: ( active: 60x ) rf: ( active: 60x )
@@ -620,7 +619,7 @@ context: Check
```Gen ```Gen
episode: Tun episode: Tun
contained_by: TUN-PRE-VGCC contained_by: VGCC-PRE-TUN
in_context: TunPreVcgg in_context: TunPreVcgg
rf: ( active: x ) rf: ( active: x )
@@ -630,21 +629,21 @@ episode: Tun
trace: trace:
``` ```
## BEH-PRE-VGCC: Container ## VGCC-PRE: Container
Voltage-Controlled Gated Channels: Qui per ora non gestiamo l'evoluzione della depolarizzazione. Alla scomparsa dell'AP, i VGCC smettono di funzionare. Voltage-Controlled Gated Channels: Qui per ora non gestiamo l'evoluzione della depolarizzazione. Alla scomparsa dell'AP, i VGCC smettono di funzionare.
```Gen ```Gen
container: BEH-PRE-VGCC container: VGCC-PRE
tub_intricated: tub_intricated:
- Ca2+ ( contained_by: BEH-PRE ) - Ca2+ ( contained_by: PRESYNAPSE )
context_intricated: context_intricated:
- AP ( contained_by: BEH-SOMA ) - AP ( contained_by: BEH-SOMA )
``` ```
### ms: behavior VGCC ### ms: behavior
#### Ca2+enter #### Ca2+enter
@@ -670,7 +669,7 @@ Devo controllare che le condizioni sotto siano esaustive.
```Gen ```Gen
episode: Ca2+enterOpen episode: Ca2+enterOpen
contained_by: BEH-PRE-VGCC contained_by: VGCC-PRE
in_context: AP in_context: AP
rf: ( active: 6x ) rf: ( active: 6x )
@@ -684,7 +683,7 @@ episode: Ca2+enterOpen
```Gen ```Gen
episode: Ca2+enterReduced-partial episode: Ca2+enterReduced-partial
contained_by: BEH-PRE-VGCC contained_by: VGCC-PRE
in_context: AP in_context: AP
rf: ( active: 6x ) rf: ( active: 6x )
@@ -698,7 +697,7 @@ episode: Ca2+enterReduced-partial
```Gen ```Gen
episode: Ca2+enterSupressed episode: Ca2+enterSupressed
contained_by: BEH-PRE-VGCC contained_by: VGCC-PRE
in_context: AP in_context: AP
rf: ( active: 6x ) rf: ( active: 6x )
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