From 549ba3cee3601994effd6dfe7d72437a331ee1d8 Mon Sep 17 00:00:00 2001 From: ocrampal Date: Tue, 14 Apr 2026 15:24:01 +0200 Subject: [PATCH] cambio label aggiunta organi --- astrocyte/README.md | 0 hypothalamus/README.md | 0 neuron/axon.md | 103 ++++++++++++++++++++-------------------- tectum/README.md | 0 vertebrae/README.md | 0 winnertakeall/README.md | 0 6 files changed, 51 insertions(+), 52 deletions(-) create mode 100644 astrocyte/README.md create mode 100644 hypothalamus/README.md create mode 100644 tectum/README.md create mode 100644 vertebrae/README.md create mode 100644 winnertakeall/README.md diff --git a/astrocyte/README.md b/astrocyte/README.md new file mode 100644 index 0000000..e69de29 diff --git a/hypothalamus/README.md b/hypothalamus/README.md new file mode 100644 index 0000000..e69de29 diff --git a/neuron/axon.md b/neuron/axon.md index aaae2d9..4721e5c 100644 --- a/neuron/axon.md +++ b/neuron/axon.md @@ -2,26 +2,26 @@ Qui comprendiamo: -- BEH-AXO: Axon -- BEH-PRE: Presynapse -- BEH-VCGG: Voltage-Controlled Gated Channels +- AXON: Axon +- PRESYNAPSE: Presynapse +- VGCC-PRE: Voltage-Controlled Gated Channels -## BEH-AXO: Container +## AXON: Container -The axon does not contain specific behavior. We might add balancing of ATP within PRE later. Here we comprehend it as a “cable” transporting the AP from SOMA to Presynapse. It expands BEH-PRE which: +The axon does not contain specific behavior. We might add balancing of ATP within PRE later. Here we comprehend it as a “cable” transporting the AP from SOMA to Presynapse. It expands PRESYNAPSE which: - can be developed by DEV-PRE -- the associations between BEH-PRE, BEH-POST e BEH-SYN is performed by the module that instantiate the Neurons and the Atrocytes, for example BEH-EXH or BEH-INH from winnertakeall. +- the associations between PRESYNAPSE, BEH-POST e BEH-SYN is performed by the module that instantiate the Neurons and the Atrocytes, for example BEH-EXH or BEH-INH from winnertakeall. ```Gen -container: BEH-AXO +container: AXON - expansion: BEH-PRE ( full: 50x, active: 0x, empty: 10x ) + expansion: PRESYNAPSE ( full: 50x, active: 0x, empty: 10x ) # managed_by: BEH-EXH or BEH-INH from winnertakeall - # developed_by: DEV-AXO-BEH-PRE-TUB from DEV-N + # developed_by: DEV-AXO-PRESYNAPSE-TUB from DEV-N ``` -## BEH-PRE: Container +## PRESYNAPSE: Container **Discursive description**: @@ -177,10 +177,9 @@ The simplification impies that: --- ```Gen -container: BEH-PRE +container: PRESYNAPSE - expansion: BEH-PRE-VGCC ( full: 10x, active: 5x, empty: 2x ) - # tuned_by: TUN-PRE-VGCC from TUN.N + expansion: VGCC-PRE ( full: 10x, active: 5x, empty: 2x ) tub_local: - Ca2+ ( full: 60x, active: 30x, empty: 0x ) @@ -204,7 +203,7 @@ container: BEH-PRE ``` -### ms: behaviors PRE +### ms: behaviors #### AP-RRPConcentration: Context @@ -216,7 +215,7 @@ Questo poi per permettere la diversa contestualizzazione degli episodi di NTrele ```Gen context: AP-RRPConcentration - contained_by: BEH-PRE + contained_by: PRESYNAPSE in_context: AP rf: ( active: 60x ) @@ -234,7 +233,7 @@ Qui controlliamo la concentrazione nel contesto di un AP. ```Gen context: AP-Ca2+Concentration - contained_by: BEH-PRE + contained_by: PRESYNAPSE in_context: AP rf: ( active: 60x ) @@ -260,7 +259,7 @@ NT empty ```Gen episode: NTreleaseMaximum - contained_by: BEH-PRE + contained_by: PRESYNAPSE in_context: (Ca2+Full AND RRPFull) rf: ( active: 3x ) # Maximum @@ -276,7 +275,7 @@ Solo in questo caso NT modera! NT NOT empty ```Gen episode: NTreleaseHigh - contained_by: BEH-PRE + contained_by: PRESYNAPSE in_context: (Ca2+Full AND RRPFull) rf: ( active: 6x ) # High @@ -292,7 +291,7 @@ In tutti i casi di NT ```Gen episode: NTreleaseMediumness - contained_by: BEH-PRE + contained_by: PRESYNAPSE in_context: (Ca2+Full AND RRPMediumness) OR (Ca2+Mediumness AND RRPFull) rf: ( active: 9x ) # Mediumness @@ -308,7 +307,7 @@ In tutti i casi di NT ```Gen episode: NTreleaseLow - contained_by: BEH-PRE + contained_by: PRESYNAPSE in_context: (Ca2+Mediumness AND RRPMediumness) rf: ( active: 12x ) # Low @@ -334,7 +333,7 @@ Abbiamo il caso di clearance nel contesto di un AP e non nel contesto di AP, per ```Gen episode: AP-CaClearanceHigh - contained_by: BEH-PRE + contained_by: PRESYNAPSE in_context: Ca2+Full rf: ( active: 3x ) # High @@ -348,7 +347,7 @@ episode: AP-CaClearanceHigh ```Gen episode: AP-CaClearanceMediumness - contained_by: BEH-PRE + contained_by: PRESYNAPSE in_context: Ca2+Mediumness rf: ( active: 6x ) # mediumness @@ -362,7 +361,7 @@ episode: AP-CaClearanceMediumness ```Gen episode: NotAP-CaClearance - contained_by: BEH-PRE + contained_by: PRESYNAPSE in_context: NOT AP rf: ( active: 24x ) # Low @@ -384,7 +383,7 @@ The result is that Tr_Ca encodes not the instantaneous calcium level but the rec ```Gen episode: CaTracesAccumulationFast - contained_by: BEH-PRE + contained_by: PRESYNAPSE in_context: Ca2+Full rf: ( active: 12x ) # fast @@ -398,7 +397,7 @@ episode: CaTracesAccumulationFast ```Gen episode: CaTracesAccumulationSlow - contained_by: BEH-PRE + contained_by: PRESYNAPSE in_context: Ca2+Full rf: ( active: 24x ) # Slow @@ -408,7 +407,7 @@ episode: CaTracesAccumulationSlow trace: None ``` -### sec: behaviors PRE +### sec: behaviors #### CheckConditionsPreSec: Context @@ -416,7 +415,7 @@ Contestualizziamo in maniera Fixed ogni mezzo secondo? ```Gen context: CheckConditionsPreSec - contained_by: BEH-PRE + contained_by: PRESYNAPSE in_context: Fixed rf: ( active: 600x ) @@ -431,7 +430,7 @@ context: CheckConditionsPreSec out_context: eCBNotEmpty ``` -#### eCB clearance +#### eCB clearance: Episode eCB dipende da POST. Tende a modulare l'entrata di Ca2+ degli VGCC. @@ -439,7 +438,7 @@ Qui non facciamo un flush di eCB, riduciamo ogni mezzo secondo (context) di un R ```Gen episode: eCBClearance - contained_by: BEH-PRE + contained_by: PRESYNAPSE in_context: eCBNotEmpty rf: ( active: 24x ) # Slow @@ -449,13 +448,13 @@ episode: eCBClearance trace: None ``` -#### CaTraces clearance +#### CaTraces clearance: Episode Qui non facciamo un flush di Catrace, riduciamo ogni mezzo secondo (context) di un RF di questo episodio. ```Gen episode: CaTracesClearance - contained_by: BEH-PRE + contained_by: PRESYNAPSE in_context: CaTracesNotEmpty rf: ( active: 24x ) # Slow @@ -477,7 +476,7 @@ Rate: 0.00 – 0.25 ```Gen episode: RPShuttleSlow - contained_by: BEH-PRE + contained_by: PRESYNAPSE in_context: RPShuttle rf: ( active: 48x ) # Slow @@ -495,7 +494,7 @@ Rate: 0.50 – 0.97 ```Gen episode: RPShuttleModerate - contained_by: BEH-PRE + contained_by: PRESYNAPSE in_context: RPShuttle rf: ( active: 24x ) # Slow @@ -516,7 +515,7 @@ Rate: 1.25 – 1.94 ```Gen episode: RPShuttleFast - contained_by: BEH-PRE + contained_by: PRESYNAPSE in_context: RPShuttle rf: ( active: 12x ) # Fast @@ -536,7 +535,7 @@ Rate: 2.50 – 5.00 ```Gen episode: RPShuttleMaximal - contained_by: BEH-PRE + contained_by: PRESYNAPSE in_context: RPShuttle rf: ( active: 6x ) # Maximal @@ -546,7 +545,7 @@ episode: RPShuttleMaximal trace: None ``` -### min: behaviors PRE +### min: behaviors #### Refill RP from Glutamine @@ -578,19 +577,19 @@ Gln — depletes over bursts, refilled by glucose (slowest, astrocyte-depend Each tier buys time for the one below it to respond. When all three are depleted simultaneously — which only happens under prolonged high-frequency firing with insufficient glucose — the synapse has no remaining buffer and goes silent until the minutes loop restores the Glutamine_pool. -#### TUN-PRE-VGCC: Tuner +#### VGCC-PRE-TUN: Tuner ```Gen -Tuner: TUN-PRE-VGCC +tuner: VGCC-PRE-TUN - contained_by: BEH-PRE + contained_by: PRESYNAPSE - tunes: BEH-PRE/expansion/BEH-PRE-VCGG + tunes: PRESYNAPSE/expansion/PRESYNAPSE-VCGG tub_modulation: # in TUN agiamo su POS/ACT - - posMod ( fullness: None, active: BEH-PRE-VCGG/fullness, empty: 0x) # riferimento a possible di BEH-PRE-VCGG - - actMod ( fullness: None, active: BEH-PRE-VCGG/active, empty: BEH-PRE-VCGG/emptiness) # riferimento a active di BEH-PRE-VCGG -# qui stiamo modulando possible e actual di BEH-PRE-VCGG associandoli + - posMod ( fullness: None, active: PRESYNAPSE-VCGG/fullness, empty: 0x) # riferimento a possible di PRESYNAPSE-VCGG + - actMod ( fullness: None, active: PRESYNAPSE-VCGG/active, empty: PRESYNAPSE-VCGG/emptiness) # riferimento a active di PRESYNAPSE-VCGG +# qui stiamo modulando possible e actual di PRESYNAPSE-VCGG associandoli # a posMod e actMod. Non serve associare una fullness perche' # la modulazione e' una pompa fra posMod e actMod e controlliamo # solo empty @@ -607,7 +606,7 @@ Tuner: TUN-PRE-VGCC ```Gen context: Check - contained_by: TUN-PRE-VGCC + contained_by: VGCC-PRE-TUN in_context: TunPossible rf: ( active: 60x ) @@ -620,7 +619,7 @@ context: Check ```Gen episode: Tun - contained_by: TUN-PRE-VGCC + contained_by: VGCC-PRE-TUN in_context: TunPreVcgg rf: ( active: x ) @@ -630,21 +629,21 @@ episode: Tun trace: ``` -## BEH-PRE-VGCC: Container +## VGCC-PRE: Container Voltage-Controlled Gated Channels: Qui per ora non gestiamo l'evoluzione della depolarizzazione. Alla scomparsa dell'AP, i VGCC smettono di funzionare. ```Gen -container: BEH-PRE-VGCC +container: VGCC-PRE tub_intricated: - - Ca2+ ( contained_by: BEH-PRE ) + - Ca2+ ( contained_by: PRESYNAPSE ) context_intricated: - AP ( contained_by: BEH-SOMA ) ``` -### ms: behavior VGCC +### ms: behavior #### Ca2+enter @@ -670,7 +669,7 @@ Devo controllare che le condizioni sotto siano esaustive. ```Gen episode: Ca2+enterOpen - contained_by: BEH-PRE-VGCC + contained_by: VGCC-PRE in_context: AP rf: ( active: 6x ) @@ -684,7 +683,7 @@ episode: Ca2+enterOpen ```Gen episode: Ca2+enterReduced-partial - contained_by: BEH-PRE-VGCC + contained_by: VGCC-PRE in_context: AP rf: ( active: 6x ) @@ -698,7 +697,7 @@ episode: Ca2+enterReduced-partial ```Gen episode: Ca2+enterSupressed - contained_by: BEH-PRE-VGCC + contained_by: VGCC-PRE in_context: AP rf: ( active: 6x ) diff --git a/tectum/README.md b/tectum/README.md new file mode 100644 index 0000000..e69de29 diff --git a/vertebrae/README.md b/vertebrae/README.md new file mode 100644 index 0000000..e69de29 diff --git a/winnertakeall/README.md b/winnertakeall/README.md new file mode 100644 index 0000000..e69de29