6.9 KiB
6.9 KiB
Table of Contents
include_toc
| include_toc |
|---|
| true |
postsynapse.md
Expansions and modulations:
- is expanded and developed by: D_BRANCH
- is tuned by: ORGANISM, organs, modules
- expands and tunes: POST-AMPA
- develops: _posMod, _actMod
POSTSYNAPSE
POSTSYNAPSE
type: comprehension
include: post_ampa.md
// ########################## Intrication ##########################
// Scope
!DAY: INTRICATE [ scope: &ORGANISM.!DAY ]
!NIGHT: INTRICATE [ scope: &ORGANISM.!NIGHT ]
// Context
*bAP: INTRICATE [ context: &SOMA.*bAP ]
*TunPossible: INTRICATE [ context: &NEURON.*TunPossible ]
// Tub
_NT: INTRICATE [ tub: &ASTROSYNAPSE._NT ]
_Vpost: INTRICATE [ tub: ??._VPost ]
// ########################## Instantiation ##########################
// Context
// Tub
_Ca2: INSTANTIATE [ tub: local, full: 60x, act: 30x, empty: 0x ]
_Na: INSTANTIATE [ tub: local, full: 60x, act: 30x, empty: 0x ]
_Nox: INSTANTIATE [ tub: local, full: 100x, act: 20x, empty: 0x ] # Nitric Oxide (NO): A gas that diffuses freely.
_eCB: INSTANTIATE [ tub: local, full: 100x, act: 20x, empty: 0x ] # Endocannabinoids (e.g., 2-AG)
_posMod: INSTANTIATE [ tub: local, full: None, act: ??, empty: 0x) # riferimento a possible di BEH-PRE
_actMod: INSTANTIATE [ tub: local, full: None, act: ??, empty: ??) # riferimento a active di BEH-PRE
// Container
void: INSTANTIATE [ scope: !DAY, container: ACTION, context: *bAP ]
void: INSTANTIATE [ scope: !DAY, container: RECOVERY, context: NOT *bAP, *Spike_train ]
void: INSTANTIATE [ scope: !DAY, container: PREPARE, context: * NOT Spike_train ]
void: INSTANTIATE [ scope: !NIGHT, container: ACTION, context: *Not_rem_1 ]
void: INSTANTIATE [ scope: !NIGHT, container: RECOVERY, context: *Not_rem_2 ]
void: INSTANTIATE [ scope: !NIGHT, container: PREPARE, context: *Rem ]
// ########################## Expansion ##########################
_@PostAmpaAll: INSTANTIATE [ tub: EXPAND [ comprehension: POST-AMPA ], full: 10x, active: 5x, empty: 2x ]
Tubs:
- _Na: Ioni entranti tramite AMPA receptors
- _NT: Neuro Trasmettitori
- _Ca2: Ioni entranti tramite NMDA
- _VPost: il voltage che viene sentito in DB
- _eCB:
- _Nox:?
!DAY | ACTION | *AP
//### MAIN_POST: !DAY
MAIN_POST
type: behaviour
within_scope: !DAY
snippet:
*bAP
@: ACCUMULATOR [ snippet: CaNDMAEnterMax, rf: active 2x ]
@: ACCUMULATOR [ snippet: CaNDMAEnterMed, rf: active 4x ]
NOT *bAP
@: ACCUMULATOR [ snippet: CaNDMAEnterLow, rf: active 12x ]
@: ACCUMULATOR [ snippet: CaNDMAEnterMedNotBap, rf: active 4x ]
@: ACCUMULATOR [ snippet: CaClearance, rf: active 24x ]
@: ACCUMULATOR [ snippet: VPostMax, rf: active 4x ]
@: ACCUMULATOR [ snippet: VPostMed, rf: active 8x ]
@: ACCUMULATOR [ snippet: VPostMin, rf: active 16x ]
@: ACCUMULATOR [ snippet: VPostClearance, rf: active 18x ]
@: ACCUMULATOR [ snippet: NaClearanceHigh, rf: active 4x ]
@: ACCUMULATOR [ snippet: NaClearanceLow, rf: active 16x ]
//#### *bAP
//##### CaNDMAEnterMax
CaNDMAEnterMax
type: accumulator
in_context: *bAP
hypothesis: NOT _Ca2 full AND
( _Na fullness OR _Na mediumness )
action: [ _Ca2 increase ]
trace:
//##### CaNDMAEnterMed
CaNDMAEnterMed
type: accumulator
in_context: *bAP
hypothesis: NOT _Ca2 full AND _Na emptiness
action: [ _Ca2 increase ]
trace:
!DAY | RECOVERY | NOT *AP, *Spike_train
//#### NOT *bAP
//##### CaNDMAEnterLow
CaNDMAEnterLow
type: accumulator
in_context: NOT *bAP
hypothesis: NOT _Ca2 full AND _Na mediumness
action: [ _Ca2 increase ]
trace:
//##### CaNDMAEnterMedNotBap
CaNDMAEnterMedNotBap
type: accumulator
in_context: NOT *bAP
hypothesis: NOT _Ca2 full AND _Na fullness
action: [ _Ca2 increase ]
trace:
//##### CaClearance
CaClearance # Low
type: accumulator
in_context: NOT *bAP
hypothesis: NOT _Ca2 empty
action: [ _Ca2 decrease ]
trace: None
//##### VPostMax
VPostMa
type: accumulator
in_context: NOT *bAP
hypothesis: _NA fullness
action: [ _VPost increase ]
trace: None
//##### VPostMed
VPostMed
type: accumulator
in_context: NOT *bAP
hypothesis: _NA mediumness
action: [ _VPost increase ]
trace: None
//##### VPostMin
VPostMin
type: accumulator
in_context: NOT *bAP
hypothesis: _NA emptiness
action: [ _VPost increase ]
trace: None
Il VPost clearance lo facciamo qui nel container dove creaiamo anche i VPost, perche' altrimenti, se lo facessimo in DB, perderemmo l'aspetto temporale della contribuzione dei singoli POST. //##### VPostClearance
VPostClearance
type: accumulator
in_context: NOT *bAP
hypothesis: NOT _VPost empty
action: [ _VPost decrease ]
trace: None
Il NA clearance lo mettiamo qui come sniplet, perche' gli AMPA creano, e questi pompano fuori. Qui non e' un problema di perdere l'integrazione temporale, perche' gli AMPA sono tutti uguali nel loro behavior. Abbiamo messo gli AMPA come container perche' cosi' possiamo modularne la numerosita'.
//##### NaClearanceHigh
NaClearanceHigh
type: accumulator
in_context: NOT *bAP
hypothesis: _Na mediumness OR _Na fullness
action: [ _Na decrease ]
trace: None
//##### NaClearanceLow
NaClearanceLow
type: accumulator
in_context: NOT *bAP
hypothesis: NOT _Na empty
action: [ _Na decrease ]
trace: None
//### TUN-POST-AMPA: !DAY
TUN-POST-AMPA
type: behaviour
activity_scope: !DAY
snippet:
# *TunPossible
@: CONTEXTOR [ snippet: CheckTunPostAmpa, rf: active 60x ]
# *TryTunUpPostAmpa
@: ACCUMULATOR [ snippet: PossibleUpPostAmpaTun, rf: active 10x ]
# *TryTunDownPostAmpa
@: ACCUMULATOR [ snippet: PossibleDownPostAmpaTun, rf: active 10x ]
//#### *TunPossible
//##### CheckTunPostAmpa
CheckTunPostAmpa
type: contextor
in_context: *TunPossible
condition: tbd1
out_context: *TryTunUpPostAmpa
condition: tbd2
out_context: *TryTunDownPostAmpa
//##### PossibleUpPostAmpaTun
PossibleUpPostAmpaTun: ( active: 10x )
type: accumulator
in_context: TryTunUpPostAmpa
hypothesis:
action:
trace:
//##### PossibleDownPostAmpaTun
PossibleDownPostAmpaTun
type: accumulator
in_context: *TryTunDownPostAmpa
hypothesis:
action:
trace: