varie
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@@ -3,11 +3,12 @@
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Qui comprendiamo:
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- PRESYNAPSE: Presynapse
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- VGCC-PRE-TUN: la modulazione della quantita' di VGCC-PRE
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- VGCC-PRE: Voltage-Controlled Gated Channels
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## PRESYNAPSE: Container
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**Simplified Behaviors**:
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**Traditional simplified Behaviors**:
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**— ms:**
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@@ -63,40 +64,6 @@ Qui riportiamo la struttura della espressione G e una descrizione di come legger
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---
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```Gen
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# G expression
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PRESYNAPSE
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AP_ctx
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ms
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NTreleaseHigh: interacting
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NTreleaseMedium: interacting
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NTreleaseLow: interacting
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AP-CaClearanceHigh: interacting
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AP-CaClearanceMedium: interacting
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NOT AP_ctx:
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ms
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NotAP-CaClearance: interacting
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CaTracesAccumulationFast: interacting
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CaTracesAccumulationSlow: interacting
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CaTracesClearance: interacting
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sec
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eCBClearance: interacting
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RPShuttleLow: interacting
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RPShuttleMedium: interacting
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RPShuttleHigh: interacting
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min
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Refill RP from Glutamine
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VGCC-PRE
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AP_ctx
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ms
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Ca2+enterLow: interacting
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Ca2+enterMedium: interacting
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Ca2+enterHigh: interacting
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```
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**Tubs:**
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- **Ca2+**: Calcium Ion entering the Presynapse when VCGG open that influence NT release. Normally returns to ~0 between spikes; stays elevated when pumps fail. They are key to check the concentration, release NT and modulation
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@@ -254,7 +221,7 @@ interacting: Ca2+TracesAccumulationHigh
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### NOT AP_ctx: PRESYNAPSE
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#### eCB clearance: int: ms
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#### eCB clearance: int: sec
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eCB dipende da POST. Tende a modulare l'entrata di Ca2+ degli VGCC.
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