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2026-05-01 12:55:13 +02:00
parent 4c4cb99711
commit b9861a3673
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@@ -3,11 +3,12 @@
Qui comprendiamo:
- PRESYNAPSE: Presynapse
- VGCC-PRE-TUN: la modulazione della quantita' di VGCC-PRE
- VGCC-PRE: Voltage-Controlled Gated Channels
## PRESYNAPSE: Container
**Simplified Behaviors**:
**Traditional simplified Behaviors**:
**— ms:**
@@ -63,40 +64,6 @@ Qui riportiamo la struttura della espressione G e una descrizione di come legger
---
```Gen
# G expression
PRESYNAPSE
AP_ctx
ms
NTreleaseHigh: interacting
NTreleaseMedium: interacting
NTreleaseLow: interacting
AP-CaClearanceHigh: interacting
AP-CaClearanceMedium: interacting
NOT AP_ctx:
ms
NotAP-CaClearance: interacting
CaTracesAccumulationFast: interacting
CaTracesAccumulationSlow: interacting
CaTracesClearance: interacting
sec
eCBClearance: interacting
RPShuttleLow: interacting
RPShuttleMedium: interacting
RPShuttleHigh: interacting
min
Refill RP from Glutamine
VGCC-PRE
AP_ctx
ms
Ca2+enterLow: interacting
Ca2+enterMedium: interacting
Ca2+enterHigh: interacting
```
**Tubs:**
- **Ca2+**: Calcium Ion entering the Presynapse when VCGG open that influence NT release. Normally returns to ~0 between spikes; stays elevated when pumps fail. They are key to check the concentration, release NT and modulation
@@ -254,7 +221,7 @@ interacting: Ca2+TracesAccumulationHigh
### NOT AP_ctx: PRESYNAPSE
#### eCB clearance: int: ms
#### eCB clearance: int: sec
eCB dipende da POST. Tende a modulare l'entrata di Ca2+ degli VGCC.