alcuni sniplet Soma e indentation
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@@ -33,6 +33,18 @@ The soma does not fire randomly or continuously. Under no input it sits at rest,
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The soma is therefore not a simple threshold device. It is a dynamic integrator with memory encoded in its current membrane potential, a nonlinear decision mechanism encoded in its channel kinetics, a refractory mechanism that shapes its temporal output, and a metabolic dependence that links its firing capacity to the health of its local environment. It is, in miniature, a complete signal processing unit — and the action potential it produces is the one binary output that all of this continuous analogue computation ultimately reduces to.
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Event Time Scale Responsible Mechanism
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─────────────────────────────────────────────────────────────────
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Resting at -70 mV steady Leak channels + pumps (balance)
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↓
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Depolarization to -50 mV ~1-2 ms Na⁺ enters (VGSCs open)
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↓
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Repolarization to -70 mV ~1-2 ms K⁺ exits (VG K⁺ channels open) ← NOT pumps!
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↓
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After-hyperpolarization ~5-20 ms K⁺ channels still open
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↓
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Return to exact -70 mV ~100-1000 ms Na⁺/K⁺ pumps restore gradients
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---
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**Simplified comprehension**:
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@@ -60,48 +72,28 @@ ATP is a simplification of convenience — at this stage we do not comprehend th
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— ms:
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- VDB is integrated (each Dendrites acts as leaky integrator)
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- Threshold check - condition VDB fullness - (only when not in AP waveform phase and not in absolute refractory)
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-- AP
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-- bAP
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-- VSOMA
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--- tau_AP_rise = 0.5 ms - Na⁺ channels open — explosive depolarisation
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--- (tau_AP_fall = 1.5 ms) - VSOMA falls toward V_AHP - K⁺ channels open — repolarisation
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--- (tau_AHP = 5.0 ms) - VSOMA recovers from V_AHP toward VSOMA_reset - K⁺ channels close — after-hyperpolarisation
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- V_bAP as a context is active during ?
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- SpikeTrainTraces ?
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-- creation
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-- destruction
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- SOMA-VCGG servono a modificare il comportamento del SOMA: refractory period.
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- threshold AP: da capire come lo modifico, forse con una modifica ad una fullness
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— seconds:
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- nothing — no slow integration in the soma
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(firing rate statistics could be computed here as a diagnostic
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but they do not feed back into any other variable)
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- Ca2+ accumulation: SpikeTrainTraces
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— mins:
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- nothing in the simplified model
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(homeostatic threshold regulation would live here if added:
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sustained low firing rate → VSOMA_threshold decreases
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sustained high firing rate → VSOMA_threshold increases
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this is the somatic equivalent of postsynaptic AMPA scaling —
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the neuron adjusts its own excitability to maintain a target
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firing rate in the face of changing input statistics)
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- VGSC modulation
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---
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**Tubs:**
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- **SpikeTrainTraces**: sono le tracce che consentono al neurone di far partire il Tuning neuronale, quando e' lontano da uno spike-train, ovvero e' in riposo.
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- **VDB**: dendrites deliver current
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- **??**: ...
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- **VSOMA**: are a proxy for the Coulombs of charge building up on the somatic membrane.
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- **AP**:
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- **bAP**:
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- **SpikeTrainTraces**: sono le tracce che consentono al neurone di far partire il Tuning neuronale, quando e' lontano da uno spike-train, ovvero e' in riposo.
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---
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@@ -126,36 +118,74 @@ container: BEH-SOMA
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- SpikeTrainTraces ( contained_by: TUN-N )
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```
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## : Context
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### ms: behaviors SOMA
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Qui mettiamo lo spike Dendritico. Sempre se vogliamo comprenderlo.
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#### CheckVDB: Context
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As dendrites deliver current (VDB), the soma acts like a capacitor. It "stores" this charge in the form of membrane potential. VSOMA is proxy for the Coulombs of charge building up on the somatic membrane.
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Contestualizziamo in maniera Fixed?
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```Gen
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context: ???...
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contained_by: BEH-SOMA
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in_context: Fixed
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rf: 60x
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condition:
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activate: xxx
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```
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## : Episode
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```Gen
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episode: ??
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context: CheckVDB
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contained_by: BEH-SOMA
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in_context: xxx
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rf: ( active: 1x )
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in_context: Fixed
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rf: ( active: 60x )
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hypothesis:
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action:
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trace: None
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condition: (VDB fullness)
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out_context: VDBMax
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condition: (VDB mediumness)
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out_context: VDBMedium
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condition: (VDB emptiness)
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out_context: VDBLow
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```
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## BEH-SOMA-VCGG: Container
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##### VDBMax: Episode
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```Gen
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episode: VDBMax
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contained_by: BEH-SOMA
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in_context: VDBMax
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rf: ( active: 2x )
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hypothesis: NOT (VSOMA full)
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action: [VSOMA increase]
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trace:
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```
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##### VDBMed: Episode
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```Gen
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episode: VDBMed
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contained_by: BEH-SOMA
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in_context: VDBMedium
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rf: ( active: 4x )
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hypothesis: NOT (VSOMA full)
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action: [VSOMA increase]
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trace:
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```
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##### VDBLow: Episode
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```Gen
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episode: VDBLow
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contained_by: BEH-SOMA
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in_context: VDBLow
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rf: ( active: 8x )
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hypothesis: NOT (VSOMA full)
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action: [VSOMA increase]
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trace:
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```
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## BEH-SOMA-VGSC: Container
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Voltage Gated Sodium Channel
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@@ -164,7 +194,9 @@ container: BEH-SOMA-VGSC
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```
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### Episode1
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### ms: behaviors SOMA-VGSC
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#### Episode1
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```Gen
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episode: ??
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