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Sergio Marchetti
2026-05-02 18:27:35 +00:00
parent c7b35af67f
commit 51098e995a
1 changed files with 83 additions and 134 deletions
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@@ -44,36 +44,36 @@ POSTSYNAPSE
bAP_ctx bAP_ctx
ms ms
-- Ca Influx -- Ca Influx
CaNDMAEnterMax: interacting CaNDMAEnterMax: accumulator
CaNDMAEnterMed: interacting CaNDMAEnterMed: accumulator
NOT bAP_ctx: NOT bAP_ctx:
ms ms
-- Ca Influx -- Ca Influx
CaNDMAEnterMedNotBap: interacting CaNDMAEnterMedNotBap: accumulator
CaNDMAEnterLow: interacting CaNDMAEnterLow: accumulator
-- Ca Clearence -- Ca Clearence
CaClearance: interacting CaClearance: accumulator
-- V Influx -- V Influx
VPostMax: interacting VPostMax: accumulator
VPostMed: interacting VPostMed: accumulator
VPostLow: interacting VPostLow: accumulator
-- V Clearence -- V Clearence
VPostClearance: interacting VPostClearance: accumulator
POST-AMPA POST-AMPA
NOT bAP_ctx NOT bAP_ctx
ms ms
-- Na Influx -- Na Influx
NaAMPAEnterMax: interacting NaAMPAEnterMax: accumulator
NaAMPAEnterMed: interacting NaAMPAEnterMed: accumulator
POST-NA-CLEAR POST-NA-CLEAR
NOT bAP_ctx NOT bAP_ctx
ms ms
-- Na Clearence -- Na Clearence
NaClearanceHigh: interacting NaClearanceHigh: accumulator
NaClearanceLow: interacting NaClearanceLow: accumulator
``` ```
@@ -89,7 +89,9 @@ POSTSYNAPSE
--- ---
```Gen ```Gen
container: POSTSYNAPSE POSTSYNAPSE
type: container
expansion: expansion:
- POST-AMPA ( full: 10x, active: 5x, empty: 2x ) - POST-AMPA ( full: 10x, active: 5x, empty: 2x )
@@ -108,190 +110,137 @@ container: POSTSYNAPSE
- VPost ( contained_by: BD ) - VPost ( contained_by: BD )
context_intricated: context_intricated:
- bAp ( contained_by: SOMA ) - bAp_ctx ( contained_by: SOMA )
``` ```
### ms: behaviors POST ### ms: behaviors POST
![post-ltp-ltd.png](.attachments/post-ltp-ltd.png) ![post-ltp-ltd.png](.attachments/post-ltp-ltd.png)
#### CheckNa: Contexting
##### CaNDMAEnterMax: Accumulator
```Gen ```Gen
context: CheckNa ## DA ELIMINARE ## CaNDMAEnterMax: ( active: 2x )
contained_by: BEH-POST
in_context: Fixed type: accumulator
rf: ( active: 60x )
condition: (Na fullness)
out_context: NaMax
condition: (Na mediumness)
out_context: NaMedium
condition: (Na emptiness)
out_context: NaLow
```
##### CaNDMAEnterMax: Interacting
```Gen
interacting: CaNDMAEnterMax
contained_by: POSTSYNAPSE contained_by: POSTSYNAPSE
in_context: bAp in_context: bAp_ctx
rf: ( active: 2x ) hypothesis: NOT (Ca2+ full) AND
(Na fullness OR Na mediumness)
hypothesis: NOT (Ca2+ full) AND action: [Ca2+ increase]
(Na fullness OR Na mediumness) trace:
action: [Ca2+ increase]
trace:
``` ```
##### CaNDMAEnterMed: Interacting ##### CaNDMAEnterMed: Accumulator
```Gen ```Gen
interacting: CaNDMAEnterMed CaNDMAEnterMed: ( active: 4x )
type: accumulator
contained_by: POSTSYNAPSE contained_by: POSTSYNAPSE
in_context: bAp in_context: bAp_ctx
rf: ( active: 4x ) hypothesis: NOT (Ca2+ full) AND (Na emptiness)
action: [Ca2+ increase]
hypothesis: NOT (Ca2+ full) AND (Na emptiness) trace:
action: [Ca2+ increase]
trace:
``` ```
##### CaNDMAEnterMedNotBap: Interacting ##### CaNDMAEnterMedNotBap: Accumulator
```Gen ```Gen
interacting: CaNDMAEnterMedNotBap CaNDMAEnterMedNotBap: ( active: 4x )
type: accumulator
contained_by: POSTSYNAPSE contained_by: POSTSYNAPSE
in_context: NOT bAP in_context: NOT bAP_ctx
rf: ( active: 4x ) hypothesis: NOT (Ca2+ full) AND (Na fullness)
action: [Ca2+ increase]
hypothesis: NOT (Ca2+ full) AND (Na fullness) trace:
action: [Ca2+ increase]
trace:
``` ```
##### CaNDMAEnterLow: Interacting ##### CaNDMAEnterLow: Accumulator
```Gen ```Gen
interacting: CaNDMAEnterLow CaNDMAEnterLow: ( active: 12x )
type: accumulator
contained_by: POSTSYNAPSE contained_by: POSTSYNAPSE
in_context: NOT bAP in_context: NOT bAP_ctx
rf: ( active: 12x ) hypothesis: NOT (Ca2+ full) AND (Na mediumness)
action: [Ca2+ increase]
hypothesis: NOT (Ca2+ full) AND (Na mediumness) trace:
action: [Ca2+ increase]
trace:
``` ```
#### CaClearance: Interacting #### CaClearance: Accumulator
```Gen ```Gen
interacting: CaClearance CaClearance: ( active: 24x ) # Low
type: accumulator
contained_by: POSTSYNAPSE contained_by: POSTSYNAPSE
in_context: NOT bAP in_context: NOT bAP_ctx
rf: ( active: 24x ) # Low hypothesis: NOT (Ca2+ empty)
action: [Ca2+ decrease]
hypothesis: NOT (Ca2+ empty) trace: None
action: [Ca2+ decrease]
trace: None
``` ```
#### CheckCaVPost:Contexting ##### VPostMax: Accumulator
Qui controlliamo il livello di Ca2+, che e' stato fatto entrare da NMDA, e creaiamo VPost nel DB. Abbiamo fatto una semplificazione, perche' il Ca2+ dovrebbe entrare nel DB in base a V_Post che fa aprire canali in DB. Invece creaimo direttamente il VPost. ##### VPostMed: Accumulator
```Gen ##### VPostMin: Accumulator
context: CheckCaVPost ### DA ELIMINARE ###
contained_by: BEH-POST
in_context: Fixed ##### VPostClearance: Accumulator
rf: ( active: 60x )
condition: (Ca2+ fullness)
out_context: CaMax
condition: (Ca2+ mediumness)
out_context: CaMedium
condition: (Ca2+ emptiness)
out_context: CaLow
```
##### VPostMax:Interacting
##### VPostMed:Interacting
##### VPostMin:Interacting
##### VPostClearance:Interacting
Il clearance lo facciamo qui nel container dove creaiamo anche i VPost, perche' altrimenti, se lo facessimo in DB, perderemmo l'aspetto temporale della contribuzione dei singoli POST. Il clearance lo facciamo qui nel container dove creaiamo anche i VPost, perche' altrimenti, se lo facessimo in DB, perderemmo l'aspetto temporale della contribuzione dei singoli POST.
## POST-AMPA: Container ## POST-AMPA: Container
```Gen ```Gen
container: POST-AMPA POST-AMPA
tub_intricated: type: container
- NT ( contained_by: SYNAPSE )
context_intricated: tub_intricated:
- Na ( contained_by: POSTSYNAPSE ) - NT ( contained_by: SYNAPSE )
context_intricated:
- Na ( contained_by: POSTSYNAPSE )
``` ```
### ms: behaviors AMPA ### ms: behaviors AMPA
#### CheckNTPost: Contexting ##### NaAMPAEnterMax: Accumulator
```Gen ```Gen
context: CheckNTPost ### DA ELIMINARE ### NaAMPAEnterMax: ( active: 2x )
type: accumulator
contained_by: POST-AMPA contained_by: POST-AMPA
in_context: NOT bAP_ctx in_context: NOT bAP_ctx
rf: ( active: 8x ) hypothesis: (NT fullness)
action: [Na increase]
condition: (NT mediumness) trace:
out_context: NTMedium
condition: (NT fullness)
out_context: NTFull
``` ```
##### NaAMPAEnterMax: Interacting ##### NaAMPAEnterMed: Accumulator
```Gen ```Gen
interacting: NaAMPAEnterMax NaAMPAEnterMed: ( active: 4x )
type: accumulator
contained_by: POST-AMPA contained_by: POST-AMPA
in_context: NOT bAP_ctx in_context: NOT bAP_ctx
rf: ( active: 2x ) hypothesis: (NT mediumness)
action: [Na increase]
hypothesis: (NT fullness) trace:
action: [Na increase]
trace:
```
##### NaAMPAEnterMed: Interacting
```Gen
interacting: NaAMPAEnterMed
contained_by: POST-AMPA
in_context: NOT bAP_ctx
rf: ( active: 4x )
hypothesis: (NT mediumness)
action: [Na increase]
trace:
``` ```
#### TUN-POST-AMPA: Tuner #### TUN-POST-AMPA: Tuner