organism/elements/neuron/d-branch.md

Table of Contents

• d-branch.md
• D-BRANCH
• MAIN_DBRANCH: !DAY
• *Fixed
• CheckVPost
• VDBClearance
• *VPostMax
• VDBMax
• *VPostMedium
• VDBMed
• *VPostLow
• VDBLow

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d-branch.md

Qui comprendiamo:

• D-BRANCH: Dendritic Branch

D-BRANCH

Simplified behaviors:

— ms:

• Each active spine contributes VPost (EPSP) to VDB
• VDB decays passively each ms

— secs:

• nothing in the simplified model

— mins:

• nothing in the simplified model
  (structural remodelling of spine neck geometry under LTP/LTD would live here if added later)

---

Intro:

• is expanded by: NEURON
• expands: POSTSYNAPSE

D-BRANCH
  type: comprehension

  include: posynapse.md
  
  expansion:
    _@postsynapse: TUB [ comprehension: POSTSYNAPSE, full: 50x, active: 0x, empty: 10x ]

  intrication:

    # Scope
    !DAY: INTRICATION [ ref: &ORGANISM.!DAY ]
    !NIGHT: INTRICATION [ ref: &ORGANISM.!NIGHT ]

    # Context
    *VPostMax: CONTEXT []
    *VPostMedium: CONTEXT []
    *VPostLow: CONTEXT []

    # Tub
    _VDB: INTRICATION [ ref: &SOMA._VDB )

  
  instantiation:

    # Tub
    _VPost: TUB [ full: 50x, active: 0x, empty: 10x ] 

    # Behaviour
    $: BEHAVIOUR [ behaviour: MAIN_DBRANCH ]

---

Tubs:

• VPost: e' l'integrazione degli EPSP della postsinapse

---

MAIN_DBRANCH: !DAY

MAIN_DBRANCH
  type: behaviour

  within_scope: !DAY

  snippet:
    # *Fixed
    @: CONTEXTOR [ snippet: CheckVPost, rf: active 60x ]
    @: ACCUMULATOR [ snippet: VDBClearance, rf: active 2x ]
    # *VPostMax
    @: ACCUMULATOR [ snippet: VDBMax, rf: active 2x ]
    # *VPostMedium
    @: ACCUMULATOR [ snippet: VDBMed, rf: active 4x ]
    # *VPostLow
    @: ACCUMULATOR [ snippet: VDBMin, rf: active 8x ]
    

*Fixed

CheckVPost

Contestualizziamo in maniera Fixed?

CheckVPost
  type: contextor
  
  in_context: *Fixed
    condition: _VPost fullness
        out_context: *VPostMax
    condition: _VPost mediumness
        out_context: *VPostMedium 
    condition: _VPost emptiness
        out_context: *VPostLow

VDBClearance

Qui facciamo il clearance del VDB. Lo facciamo in questo modo perche' abbiamo semplificato quello che succede fra BD e SOMA. Qui posso aggiungere il flush, clearance veloce quando c'e' il bAP.

VDBClearance
  in_context: *Fixed

 hypothesis: NOT _VDB empty
    action: [ _VDB decrease ] 
    trace: 

*VPostMax

VDBMax

VDBMax
  in_context: *VPostMax

  hypothesis: NOT _VDB full
    action: [ _VDB increase ]
    trace: 

*VPostMedium

VDBMed

VDBMed
  in_context: *VPostMedium

  hypothesis: NOT _VDB full
    action: [ _VDB increase ]
    trace: 

*VPostLow

VDBLow

  in_context: *VPostLow

  hypothesis: NOT _VDB full
    action: [ _VDB increase ]
    trace: