varie

2026-06-01 16:13:48 +02:00
parent 468a083e82
commit f88c08636e
2 changed files with 17 additions and 16 deletions
@@ -1,6 +1,10 @@
+---
+include_toc: true
+---
+
 # README.md

-**The astrocyte is not globally uniform — it is locally selective**:
+## Calcium wave

 The calcium wave does not behave like a uniform broadcast. It has two distinct modes:

@@ -8,7 +12,7 @@ The first is a **local microdomain response**. When a single synapse fires heavi

 The second is a **propagating wave**. When activity is sustained and intense enough, the calcium signal spreads from process to process across the astrocyte body and even into neighbouring astrocytes via gap junctions. This is the threshold event that IP3 models. Once the wave propagates, the response is no longer selective — it affects multiple synapses under that astrocyte's territory.

-**What this means for your model**:
+### Implication for the model

 Your current model simulates a single tripartite synapse — one presynapse, one postsynapse, one astrocyte process. In that context the selectivity question does not arise because there is only one synapse to serve.