aggiunto behavior ms, sec, min

This commit is contained in:
2026-03-22 11:03:33 +01:00
parent cc37afd225
commit d765205654
2 changed files with 75 additions and 18 deletions
+9 -1
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@@ -36,6 +36,14 @@ La fullness di un Tub puo' essere cambiata in DEV. Dal punto di vista della comp
L'assegnazione dei livelli di fullness, active e emptiness viene fatta una volta completata l'espansione come per RF. Infatti l'assegnazione deve essere collegata a RF. L'assegnazione dei livelli di fullness, active e emptiness viene fatta una volta completata l'espansione come per RF. Infatti l'assegnazione deve essere collegata a RF.
#### full, medium and empty
Il controllo della condition in un context o episode viene fatto con 3 "stati".
- full: se gli actual sono maggiori o uguali a fullness
- medium: se gli actual sono minori di fullness e maggiori di emptiness
- empty: se gli actual sono uguali o meno di emptiness
### RF ### RF
Teorema di Shannon inverso. E' come se facessimo un campionamento su un ipotesi di continuita'. Teorema di Shannon inverso. E' come se facessimo un campionamento su un ipotesi di continuita'.
@@ -100,4 +108,4 @@ Si tratta di 4 ragionamenti locali:
Come sopra, ma il punto 4 viene gestito da una compensione che non e' piu' il WTA (organo), ma una comprensione "superiore" che gestisce l'espansione degli organi. Tipo ORG.md. Come sopra, ma il punto 4 viene gestito da una compensione che non e' piu' il WTA (organo), ma una comprensione "superiore" che gestisce l'espansione degli organi. Tipo ORG.md.
### Presynapse ### Presynapse
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@@ -108,16 +108,23 @@ container: BEH-PRE
- CaTraces ( fullness: 50x, active: 0x, emptiness: 0x ) - CaTraces ( fullness: 50x, active: 0x, emptiness: 0x )
- mGluR ( fullness: 50x, active: 0x, emptiness: 0x )
- CDI ( fullness: 50x, active: 0x, emptiness: 0x )
tub_intricated: tub_intricated:
- NT - NT # SYN
- ATP - ATP # AXO?
- eCB # from POST
context_intricated: context_intricated:
- AP ( contained_by: BEH-SOMA ) - AP ( contained_by: BEH-SOMA )
``` ```
### RRPConcentration: Context ### ms: behavior
#### RRPConcentration: Context
Il rilascio di NT lo facciamo nel contesto di AP. Biologicamente dovrebbe avvenire solo in base alle concentrazioni, quindi anche al difuori degli AP. Il rilascio di NT lo facciamo nel contesto di AP. Biologicamente dovrebbe avvenire solo in base alle concentrazioni, quindi anche al difuori degli AP.
@@ -128,14 +135,14 @@ context: RRPConcentration
in_context: AP in_context: AP
rf: ( active: 60x ) rf: ( active: 60x )
condition: NOT (Rrp empty) AND NOT (Rrp full) condition: (Rrp medium)
out_context: RRPMedium out_context: RRPMedium
condition: (Rrp full) condition: (Rrp full)
out_context: RRPFull out_context: RRPFull
``` ```
### Ca2MicroConcentration: Context #### Ca2MicroConcentration: Context
```Gen ```Gen
context: Ca2MicroConcentration context: Ca2MicroConcentration
@@ -144,20 +151,20 @@ context: Ca2MicroConcentration
in_context: AP in_context: AP
rf: ( active: 60x ) rf: ( active: 60x )
condition: NOT (Ca2Micro empty) AND NOT (Ca2Micro full) condition: (Ca2Micro medium)
out_context: Ca2MicroMedium out_context: Ca2MicroMedium
condition: (Ca2Micro full) condition: (Ca2Micro full)
out_context: Ca2MicroFull out_context: Ca2MicroFull
``` ```
### NTrelease: Episodes #### NTrelease: Episodes
Ci sono 4 casi che dipendono da RRP, CaMicro e NT. L'idea e' che la quantita' di RRP sia il driver principale. Gli NT liberati sono di piu' al crescere di RRP e CaMicro e di meno al crescere di NT. Gli NT nella sinapsi fanno da moderazione alla ulteriore liberazione di NT, ma non bloccano mai totalmente. NT suppression only matters when everything else is already at maximum — which is exactly the biological purpose: it prevents runaway release during peak activity, not during moderate activity. Ci sono 4 casi che dipendono da RRP, CaMicro e NT. L'idea e' che la quantita' di RRP sia il driver principale. Gli NT liberati sono di piu' al crescere di RRP e CaMicro e di meno al crescere di NT. Gli NT nella sinapsi fanno da moderazione alla ulteriore liberazione di NT, ma non bloccano mai totalmente. NT suppression only matters when everything else is already at maximum — which is exactly the biological purpose: it prevents runaway release during peak activity, not during moderate activity.
ATP cost of Na/K-ATPase recharge on each AP. The cost is per action potential. Here we charge it at every release of NT. This is the dominant ATP drain at high firing rates. ATP cost of Na/K-ATPase recharge on each AP. The cost is per action potential. Here we charge it at every release of NT. This is the dominant ATP drain at high firing rates.
#### NTreleaseMaximum: Episode ##### NTreleaseMaximum: Episode
```Gen ```Gen
episode: NTreleaseMaximum episode: NTreleaseMaximum
@@ -171,7 +178,7 @@ episode: NTreleaseMaximum
trace: None trace: None
``` ```
#### NTreleaseHigh: Episode ##### NTreleaseHigh: Episode
```Gen ```Gen
episode: NTreleaseHigh episode: NTreleaseHigh
@@ -185,7 +192,7 @@ episode: NTreleaseHigh
trace: None trace: None
``` ```
#### NTreleaseMedium: Episode ##### NTreleaseMedium: Episode
```Gen ```Gen
episode: NTreleaseMedium episode: NTreleaseMedium
@@ -199,7 +206,7 @@ episode: NTreleaseMedium
trace: None trace: None
``` ```
#### NTreleaseLow: Episode ##### NTreleaseLow: Episode
```Gen ```Gen
episode: NTreleaseLow episode: NTreleaseLow
@@ -213,6 +220,22 @@ episode: NTreleaseLow
trace: None trace: None
``` ```
### sec: behavior
...
#### mGlur
#### eCB
#### CDI
#### RP->RRP
### min: behavior
#### Refill RP from Glutamine
## BEH-PRE-VGCC: Container ## BEH-PRE-VGCC: Container
**Voltage-Controlled Gated Channels**: **Voltage-Controlled Gated Channels**:
@@ -289,20 +312,46 @@ Here we comprehend the breaking activity on VGCC by: CDI,eCB and mGluR:
- **Suppressed** — two brakes multiplying. The compounding is what defines this zone — no single variable alone produces it (except CDI approaching full). 0.5 × 0.5 = 0.25 remaining is where the synapse starts losing significant transmission efficacy. Biologically this is the pre-silence warning zone: CDI is building from residual Ca²⁺ while eCB is already engaged from postsynaptic activity. - **Suppressed** — two brakes multiplying. The compounding is what defines this zone — no single variable alone produces it (except CDI approaching full). 0.5 × 0.5 = 0.25 remaining is where the synapse starts losing significant transmission efficacy. Biologically this is the pre-silence warning zone: CDI is building from residual Ca²⁺ while eCB is already engaged from postsynaptic activity.
- **Closed — CDI** = full is the only reliable hard rule. Because CDI can reach 1.0 and appears as (1 - CDI_factor) in the formula, it alone drives conductance to zero regardless of eCB and mGluR state. The three-brake overlap corner case (eCB=full + CDI=medium + mGluR=full) also reaches here, but in practice CDI reaching full is the primary biological mechanism. - **Closed — CDI** = full is the only reliable hard rule. Because CDI can reach 1.0 and appears as (1 - CDI_factor) in the formula, it alone drives conductance to zero regardless of eCB and mGluR state. The three-brake overlap corner case (eCB=full + CDI=medium + mGluR=full) also reaches here, but in practice CDI reaching full is the primary biological mechanism.
#### Ca2+enterFast: Episode Devo controllare che le condizioni sotto siano esaustive.
#### Ca2+enterMedium: Episode #### Open: Episode
#### Ca2+enterSlow: Episode
```Gen ```Gen
episode: Ca2+enter episode: Open
contained_by: BEH-PRE-VGCC contained_by: BEH-PRE-VGCC
in_context: AP in_context: AP
rf: ( active: 6x ) rf: ( active: 6x )
hypothesis: NOT (Ca2+ full) hypothesis: (CDI empty) and (eCB empty)
action: [Ca2+ increase, ATP decrease]
trace: None
```
#### Reduced-partial: Episode
```Gen
episode: Reduced-partial
contained_by: BEH-PRE-VGCC
in_context: AP
rf: ( active: 6x )
hypothesis: (CDI medium) OR ((eCB medium) AND (CDI empty)) OR ((eCB full) AND (CDI empty) AND (mGluR empty))
action: [Ca2+ increase, ATP decrease]
trace: None
```
#### Suppressed: Episode
```Gen
episode: Supressed
contained_by: BEH-PRE-VGCC
in_context: AP
rf: ( active: 6x )
hypothesis: ((CDI medium) AND (eCB full) OR (eCB medium))
action: [Ca2+ increase, ATP decrease] action: [Ca2+ increase, ATP decrease]
trace: None trace: None
``` ```