Update 2026-06-02-astrocyte-behaviors.md

2026-06-04 10:13:51 +02:00
parent 6096202642
commit cd374bd8b6
1 changed files with 4 additions and 0 deletions
@@ -6,6 +6,10 @@ include_toc: true

 This document compiles the complete, integrated framework of your tripartite synapse model. It translates the biological interactions of the **presynapse**, **postsynapse**, **astrocyte**, and **neuromodulators** into a singular, high-level metaphor of **wave propagation, resonance, and acoustic carving** across multiple time scales.

+## Intro
+
+The presynapse, postsynapse, and astrocyte each maintain a **default low-energy baseline** when input frequency is within normal range (~1–10 Hz): the presynapse releases vesicles at low probability, the postsynapse stays clamped by the Mg²⁺ block, and the astrocyte simply clears the cleft and ticks over its fuel pipeline. When current input deviates from this baseline — either upward into high-frequency bursts or downward into disuse — the system begins to adapt, but the *direction* of that adaptation depends on **past influence**: if the high-frequency drive is sustained and coincides with a neuromodulatory validation signal (dopamine), the deviation gets permanently encoded as structural expansion; if the drive is transient, only temporary facilitation occurs and the system rebounds; if the signal is chronically weak or mistimed, the astrocyte actively dissolves the existing structure and the synapse contracts back toward silence. In other words, current input sets the *alarm*, but accumulated history — stored in vesicle pool sizes, receptor counts, and ECM integrity — determines whether the response is ignored, temporarily buffered, permanently carved in, or actively erased.
+
 ---

 ## 1. The Cast of the Acoustic Chamber