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2026-03-21 12:42:59 +01:00
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neuron/BEH-AXO.md
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@@ -32,7 +32,7 @@ container: BEH-AXO
**Fast — 1 ms**: **Fast — 1 ms**:
- AP fires → membrane jumps to peak, decays toward rest (Na/K-ATPase recharge). Here we do not comprehend the decay. - AP fires → membrane jumps to peak, decays toward rest (Na/K-ATPase recharge). Here we do not comprehend the decay.
- ATP cost charged per AP - ATP cost charged per AP (Here we can comprehend it with an integrator)
- Ca²⁺ enters via VGCCs, gated by CDI, eCB, and mGluR suppression - Ca²⁺ enters via VGCCs, gated by CDI, eCB, and mGluR suppression
- ATP cost charged per unit Ca²⁺ cleared. Here we charge per Ca2+ entered - ATP cost charged per unit Ca²⁺ cleared. Here we charge per Ca2+ entered
- CDI rises with Ca²⁺, recovers when Ca²⁺ is low - CDI rises with Ca²⁺, recovers when Ca²⁺ is low
@@ -151,13 +151,13 @@ context: Ca2MicroConcentration
out_context: Ca2MicroFull out_context: Ca2MicroFull
``` ```
### NTrelease episodes ### NTrelease: Episodes
Ci sono 4 casi che dipendono da RRP, CaMicro e NT. L'idea e' che la quantita' di RRP sia il driver principale. Gli NT liberati sono di piu' al crescere di RRP e CaMicro e di meno al crescere di NT. Gli NT nella sinapsi fanno da moderazione alla ulteriore liberazione di NT, ma non bloccano mai totalmente. NT suppression only matters when everything else is already at maximum — which is exactly the biological purpose: it prevents runaway release during peak activity, not during moderate activity. Ci sono 4 casi che dipendono da RRP, CaMicro e NT. L'idea e' che la quantita' di RRP sia il driver principale. Gli NT liberati sono di piu' al crescere di RRP e CaMicro e di meno al crescere di NT. Gli NT nella sinapsi fanno da moderazione alla ulteriore liberazione di NT, ma non bloccano mai totalmente. NT suppression only matters when everything else is already at maximum — which is exactly the biological purpose: it prevents runaway release during peak activity, not during moderate activity.
ATP cost of Na/K-ATPase recharge on each AP. The cost is per action potential. Here we charge it at every release of NT. This is the dominant ATP drain at high firing rates. ATP cost of Na/K-ATPase recharge on each AP. The cost is per action potential. Here we charge it at every release of NT. This is the dominant ATP drain at high firing rates.
#### NTreleaseMaximum episodes #### NTreleaseMaximum: Episode
```Gen ```Gen
episode: NTreleaseMaximum episode: NTreleaseMaximum
@@ -171,7 +171,7 @@ episode: NTreleaseMaximum
trace: None trace: None
``` ```
#### NTreleaseHigh episodes #### NTreleaseHigh: Episode
```Gen ```Gen
episode: NTreleaseHigh episode: NTreleaseHigh
@@ -185,7 +185,7 @@ episode: NTreleaseHigh
trace: None trace: None
``` ```
#### NTreleaseMedium episodes #### NTreleaseMedium: Episode
```Gen ```Gen
episode: NTreleaseMedium episode: NTreleaseMedium
@@ -199,7 +199,7 @@ episode: NTreleaseMedium
trace: None trace: None
``` ```
#### NTreleaseLow episodes #### NTreleaseLow: Episode
```Gen ```Gen
episode: NTreleaseLow episode: NTreleaseLow
@@ -227,3 +227,17 @@ container: BEH-PRE-VGCC
context_intricated: context_intricated:
- AP ( contained_by: BEH-SOMA ) - AP ( contained_by: BEH-SOMA )
``` ```
### Ca2+enter: Episode
```Gen
episode: Ca2+enter
contained_by: BEH-PRE-VGCC
in_context: AP
rf: ( active: 6x )
hypothesis: NOT (Ca2+ full)
action: [Ca2+ increase, ATP decrease]
trace: None
```