From 9c7ce96ff8acd7a422bc43240c5a94e8a692d8f8 Mon Sep 17 00:00:00 2001 From: ocrampal Date: Mon, 20 Apr 2026 12:10:31 +0200 Subject: [PATCH] unito vari context --- neuron/soma.md | 64 ++++++++++++++++++++++++++++---------------------- 1 file changed, 36 insertions(+), 28 deletions(-) diff --git a/neuron/soma.md b/neuron/soma.md index 8472af2..f7c6cf1 100644 --- a/neuron/soma.md +++ b/neuron/soma.md @@ -101,45 +101,39 @@ container: SOMA ### ms: SOMA -#### VDB-Concentration: check_tpc +#### SOMA-Status: check_tpc As dendrites deliver current (VDB​), the soma acts like a capacitor. It "stores" this charge in the form of membrane potential. This contextualizes VGSC-SOMA to open ion channels that let Na+ ions in. This only applies if not ApCtx, or in other words, SOMA is not in refractory period. ```Gen -check_tpc: VDB-Concentration +check_tpc: SOMA-Status contained_by: SOMA - tpc: any + in_context: any rf: ( active: 60x ) - condition: (VDB fullness ) AND NOT ApCtx - out_tpc: VDBMaxCtx + condition: ( VDB fullness ) AND NOT ApCtx + out_context: VDBMaxCtx condition: ( VDB mediumness ) AND NOT ApCtx - out_tpc: VDBMediumCtx + out_context: VDBMediumCtx condition: ( VDB emptiness ) AND NOT ApCtx - out_tpc: VDBLowCtx -``` + out_context: VDBLowCtx -#### SomaSpill: interacting + condition: NOT ( Na empty ) + out_context: NaSpill_ctx -```Gen -interacting: SomaSpill - contained_by: SOMA - - context: any - rf: ( active: 8x ) - - hypothesis: NOT NA emptiness - action: [ decrease NA ] - trace: + condition: NOT ( RefractorySoma empty ) + out_context: RefractorySoma_ctx ``` #### SomaSpike: check_tpc +Il fatto che mettiamo il check di AP separato dal check del Soma-Status, e' perche' vogliamo poter avere un RF specifico per AP, eventualmente tunabile. + Qui siamo nella fase effettiva di spike, non refractory che viene dopo. Fa da contesto di durata fra un RF ed un altro. La fullness di Na rappresenta il threshold e puo' essere modificato. La fullness di RefractorySoma rappresenta la lunghezza del refractory. @@ -148,23 +142,23 @@ La fullness di Na rappresenta il threshold e puo' essere modificato. La fullness check_tpc: SomaSpike contained_by: SOMA - context: fixed - rf: ( active: 60x ) + in_context: any + rf: ( active: 30x ) condition: ( Na fullness ) AND ( RefractorySoma emptiness ) out_context: ApCtx out_context: bApCtx ``` -#### ApBeh: interacting +#### ActiveAP: interacting Durante la fase effettiva di spike, eliminiamo Na accumulati, riempiamo RefractorySoma per fase di refractory e riempiamo Ca2+ per le tracce medio termine di potenziamento/depotenziamento. ```Gen -interacting: ApBeh +interacting: ActiveAP contained_by: SOMA - context: ApCtx + in_context: ApCtx rf: ( active: 8x ) hypothesis: NOT Na empty @@ -180,18 +174,32 @@ interacting: ApBeh trace: ``` -#### RefractorySpill: interacting +#### NaSpill: interacting + +```Gen +interacting: NaSpill + contained_by: SOMA + + in_context: NaSpill_ctx + rf: ( active: 8x ) + + hypothesis: NOT ( Na emptiness ) + action: [ decrease Na ] + trace: +``` + +#### RefractorySomaSpill: interacting Lo spill deve essere piu' lento dell'increase che avviene in APBeh ```Gen -interacting: RefractorySpill +interacting: RefractorySomaSpill contained_by: SOMA - context: any + in_context: RefractorySoma_ctx rf: ( active: 16x ) - hypothesis: NOT RefractorySoma empty + hypothesis: NOT ( RefractorySoma empty ) action: [ decrease RefractorySoma ] trace: ```