post

README.md

@@ -28,6 +28,8 @@ C'e' una differenza se il cambio di fullness e' su un Tub di tipo floor (esempio
 
 Il context e' a RF piu' alto, che attiva la possibilita' di un episode a RF piu' basso. L'episode "dura" in un intervallo di context. Il context puo' integrare le ipotesi fatte durante l'episode.
 
+A Context sets the conditions, an Episode is a named outcome within those conditions.
+
 ### Condition, hypothesis
 
 ...

neuron/BEH-AXO.md

@@ -198,7 +198,7 @@ container: BEH-PRE
 
 ```
 
-### ms: behaviors
+### ms: behaviors PRE
 
 #### AP-RRPConcentration: Context
 
@@ -402,14 +402,14 @@ episode: CaTracesAccumulationSlow
     trace: None
 ```
 
-### sec: behaviors
+### sec: behaviors PRE
 
-#### SecContext: Context
+#### CheckConditions: Context
 
 Contestualizziamo in maniera Fixed ogni mezzo secondo?
 
 ```Gen
-context: SecContext
+context: CheckConditions
   contained_by: BEH-PRE
 
   in_context: Fixed
@@ -540,7 +540,7 @@ episode: RPShuttleMaximal
     trace: None
 ```
 
-### min: behaviors
+### min: behaviors PRE
 
 #### Refill RP from Glutamine
 

neuron/BEH-BD.md

@@ -15,7 +15,7 @@ Qui BEH-DB espande solo i BEH-POST, e' un cavo di collegamento come l'assone
 Container: BEH-BD
  
  expansion:
-  - BEH-POST ( fullness: 50x, active: 20x, emptiness: 10x ) 
+  - BEH-POST ( full: 50x, active: 20x, empty: 10x ) 
     modulated_by: DEV-BD-BEH-POST-TUB from DEV-N.md
 ```
 
@@ -27,7 +27,7 @@ Like its presynaptic partner, the postsynapse is governed by three interlocking
 
 ---
 
-### 1. The $V_{post}$ Loop: The Fast Gatekeeper (Milliseconds)
+1.The $V_{post}$ Loop: The Fast Gatekeeper (Milliseconds)
 
 This is the primary electrophysiological response, where chemical signals are converted back into electricity.
 
@@ -39,7 +39,7 @@ This is the primary electrophysiological response, where chemical signals are co
 
 ---
 
-### 2. The $Ca^{2+}$ Loop: The Plasticity Controller (Seconds)
+2.The $Ca^{2+}$ Loop: The Plasticity Controller (Seconds)
 
 This loop translates electrical timing into biological "memory."
 
@@ -51,7 +51,7 @@ This loop translates electrical timing into biological "memory."
 
 ---
 
-### 3. The ATP Loop: The Metabolic Backbone (Minutes)
+3.The ATP Loop: The Metabolic Backbone (Minutes)
 
 This is the "Hidden Master" that determines if the other two loops are allowed to function.
 
@@ -71,36 +71,46 @@ The system is beautifully asymmetric. While the presynapse is built to **supply*
 container: BEH-POST
 
  expansion: 
-  - BEH-POST-AMPA ( fullness: 10x, active: 5x, emptiness: 2x )
+  - BEH-POST-AMPA ( full: 10x, active: 5x, empty: 2x )
    # modulated_by: TUN-POST-IC # possible/actual
 
  tub_local:
-  - Ca2+ ( fullness: 60x, active: 30x, emptiness: 0x )
+  - Ca2+ ( full: 60x, active: 30x, empty: 0x )
    # modulated_by: DEV-POST-???-FULL # Full 
 
-  - Nox ( fullness: 100x, active: 20x, emptiness: 0x ) # Nitric Oxide (NO):  A gas that diffuses freely.
+  - Nox ( full: 100x, active: 20x, empty: 0x ) # Nitric Oxide (NO):  A gas that diffuses freely.
 
-  - Ecb ( fullness: 100x, active: 20x, emptiness: 0x ) # Endocannabinoids (e.g., 2-AG)
+  - Ecb ( full: 100x, active: 20x, empty: 0x ) # Endocannabinoids (e.g., 2-AG)
 
  tub_intricated:
   - Nt ( contained_by: BEH-SYN )
   - bAp ( contained_by: BEH-SOMA )
 ```
 
-### Context
+### ms: behaviors POST
+
+#### CheckConditions:Context
+
+Contestualizziamo in maniera Fixed ogni mezzo secondo?
 
 ```Gen
-context: captureNt
+context: CheckConditions
   contained_by: BEH-POST
 
   in_context: Fixed
- rf: ( active: 10x )
+  rf: ( active: 600x )
 
- condition: (Nt full) AND NOT (bAp)
-  out_context: NtCaptured
+  condition: NOT (RP empty) AND NOT (RRP full)
+    out_context: RPShuttle
+
+  condition: NOT (CaTrace empty) 
+    out_context: CaTracesNotEmpty
+
+  condition: NOT (eCB empy) 
+    out_context: eCBNotEmpty
 ```
 
-### Episode
+#### :Episode
 
 ## BEH-POST-AMPA: Container
 
@@ -114,7 +124,13 @@ container: BEH-POST-AMPA
   - bAp ( contained_by: BEH-SOMA )
 ```
 
-### AmpaOpen: Episode
+### sec: behaviors POST
+
+### min: behaviors POST
+
+### ms: behaviors AMPA
+
+#### AmpaOpen: Episode
 
 - Timing: < 1 ms
 - InContext: Glutamate > FULLNESS
@@ -134,7 +150,7 @@ episode: AmpaOpen
   trace: None # Se Ca+FULLNESS, lascio tracce di overflow per modulazione DOWN, da capire UP
 ```
 
-### Depolarization by bAP
+#### Depolarization by bAP
 
 Da ricordare i Dendritic VCGG che si aprono facendo entrare Ca2+ all'arrivo di bAP. In teoria abbiamo 3 Ion Channel.
 
@@ -142,23 +158,23 @@ Da ricordare i Dendritic VCGG che si aprono facendo entrare Ca2+ all'arrivo di b
 - InContext: bAP backpropagating action potential
 - Consequence: addition to local depolarization (EPSP) from bAP
 
-### Mg²⁺ NMDA unblock
+#### Mg²⁺ NMDA unblock
 
 - Timing: > 1 ms
 - InContext: local depolarization (EPSP) > FULLNESS (requires depolarization > -40mV)
 - OutContext: NMDA Mg²⁺ unblock
 
-### Full Ca+ influx by NDMA
+#### Full Ca+ influx by NDMA
 
 - Timing: < 1 ms
 - InContext: NMDA Mg²⁺ unblock
 - Consequence: Na⁺ influx
 - Consequence: addition to local depolarization (EPSP) from Full NMDA activation
 
-### Upregulation: Observable
+#### Upregulation: Observable
 
 - Upregulation: Depolarization relieves NMDA Mg²⁺ block → Ca²⁺ influx amplification
 
-### Downregulation: Observable
+#### Downregulation: Observable
 
 - Downregulation: AMPA desensitization acts as low-pass filter

neuron/appunti/2026-03-30-behavior-POST.md

@@ -1,91 +1,299 @@
-## BEH-POST-UNIFIED: The Integrated Postsynaptic Model
+---
 
-### **ms: behaviors (Fast Kinetics & Gate Logic)**
+**What needs adjustment**
 
-#### **Voltage-Context: Episode**
+`Voltage-Context` is labelled as an Episode but contains sub-episodes — it should be a Context. Same for `NMDA-Coincidence` and `Ca-Dynamics & ATP-Drain`. You have used Episode and Context interchangeably in a few places; the distinction matters for the specification: a Context sets the conditions, an Episode is a named outcome within those conditions.
 
-*Determines the total depolarization level (Vpost​) available to clear the NMDA Mg-block.*
+`Vpost_Maximum` lists `V_bAP full OR (g_AMPA full AND V_bAP medium)` — this is correct Boolean logic and should be kept exactly as written. It captures the two ways the postsynapse can reach maximum depolarisation: the bAP alone if it is strong enough, or AMPA plus a partial bAP together.
 
-- **Vpost_Maximum: Episode**
-  - — `V_bAP` full OR (`g_AMPA` full AND `V_bAP` medium)
-  - — Result: Vpost​ is high enough for complete Mg-block removal.
-- **Vpost_Attenuated: Episode**
-  - — `g_AMPA` medium AND `V_bAP` empty/low
-  - — Result: Vpost​ is sub-threshold; Mg-block partially remains.
-- **Vpost_Passive: Episode**
-  - — `g_AMPA` empty AND `V_bAP` empty
-  - — Result: Vpost​ at rest; Mg-block fully intact.
+`AMPA_Population_Increase` correctly gates on `ATP_level_post NOT empty` — LTP requires ATP for CaMKII phosphorylation and receptor trafficking. LTD does not have the same gate in your spec. This is slightly asymmetric — LTD (receptor internalisation via endocytosis) is also ATP-dependent, though less so than LTP. Worth noting.
 
-#### **NMDA-Coincidence: Context**
+`Plasticity_LTD` covers `Ca_post_history medium` but does not cover the case where `Ca_post_history` is empty — a completely silent synapse also weakens over time (homeostatic depression). This can be left as a gap or named explicitly.
 
-- **NMDA_Open: Episode**
-  - — `NT_cleft` full AND `V_post` maximum
-  - — Result: Capost​ surges; triggers high ATP demand for clearance.
-- **NMDA_LogicBlocked: Episode**
-  - — `NT_cleft` full BUT `V_post` attenuated/passive
-  - — Result: Mg-block prevents Ca2+ influx despite NT presence.
-- **NMDA_LigandBlocked: Episode**
-  - — `V_post` maximum BUT `NT_cleft` empty
-  - — Result: No glutamate to open the channel; Ca2+ entry zero.
+`Astrocyte_Supply_Crises` has a typo (Crises → Crisis).
 
-#### **Ca-Dynamics & ATP-Drain: Context**
-
-- **Clearance_Optimal: Episode**
-  - — `ATP_level_post` full
-  - — Result: Pumps flush Ca2+ rapidly; `ATP_demand_post` increases.
-- **Clearance_Failing: Episode**
-  - — `ATP_level_post` low/empty
-  - — Result: Ca2+ remains elevated (residual floor); creates "False Trigger" conditions.
+The bAP needs new parameters and state variables in the model before it can be expressed as a fully implemented behavior. I will add those inline as `[GAP — to implement]` markers so the spec is complete even where the code is not yet written.
 
 ---
 
-### **sec: behaviors (Signal Integration & Fate)**
+**Final restructured specification**
 
-#### **Synaptic-Weight-Decision (Plasticity)**
+```
+BEH-POST-UNIFIED: The Integrated Postsynaptic Model
+=====================================================
+Three loops, three timescales, one shared astrocyte supply.
+Each loop feeds the next: V_post enables NMDA, NMDA drives
+Ca_post, Ca_post determines plasticity and eCB, ATP sustains
+all three. Failure of ATP does not silence the postsynapse
+(unlike the presynapse) — it corrupts it, triggering false
+retrograde signals and risking excitotoxic Ca2+ accumulation.
 
-- **Plasticity_LTP: Episode**
-  - — `Ca_post_history` (recent 2s) is **Full**
-  - — Result: High-frequency/High-amplitude coincidence detected; tags synapse for AMPA increase.
-- **Plasticity_LTD: Episode**
-  - — `Ca_post_history` is **Medium**
-  - — Result: Low-frequency or poorly timed coincidence; tags synapse for AMPA removal.
+Variables:
+  V_bAP              — back-propagating AP amplitude (0→1)
+                       [GAP — requires bAP_train input,
+                        analogous to presynaptic spike_train]
+  g_AMPA             — AMPA receptor conductance (= receptor_conductance)
+  V_post             — total postsynaptic membrane potential (0→1)
+  NT_cleft           — glutamate in cleft (from presynapse)
+  Desensitization    — fraction of AMPA receptors desensitized (0→1)
+  Ca_post            — free Ca2+ in postsynaptic spine (0→...)
+  Ca_post_history    — 2 s rolling mean of Ca_post
+  ATP_level_post     — normalised postsynaptic ATP (0→1)
+  ATP_demand_post    — accumulated ATP cost since last metabolic cycle
+  g_AMPA_baseline    — long-term AMPA receptor density set by plasticity
+                       [GAP — not yet in model; LTP/LTD would write this]
+  eCB_level          — endocannabinoid retrograde signal (0→1)
+                       written here, read by presynapse Loop 1
 
-#### **Retrograde-Feedback (eCB)**
+━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━
+ms: behaviors — Fast Kinetics and Gate Logic
+━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━
 
-- **eCB_Synthesis_Active: Episode**
-  - — `Ca_post_history` > threshold (0.7)
-  - — **Logic A (Protection):** Response to genuine NMDA over-activity.
-  - — **Logic B (Error):** Response to pump failure (Ca2+ accumulation due to low ATP).
-- **eCB_Synthesis_Idle: Episode**
-  - — `Ca_post_history` < threshold; eCB level decays.
+Voltage-Context: Context
+  Determines the total depolarisation (V_post) available to
+  lift the NMDA Mg block. Two independent sources contribute:
+  AMPA-driven local depolarisation (g_AMPA) and the somatic
+  back-propagating AP (V_bAP). Either alone can partially
+  depolarise; both together reach maximum.
 
----
+  Vpost_Maximum: Episode
+    — V_bAP full                          OR
+    — g_AMPA full AND V_bAP medium
+    — Result: V_post high enough for complete Mg block removal.
+              NMDA gate can open fully.
+              Both ATP costs charged at maximum rate.
 
-### **min: behaviors (Bioenergetics & Structural Change)**
+  Vpost_Attenuated: Episode
+    — g_AMPA medium AND V_bAP empty/low   OR
+    — g_AMPA low AND V_bAP medium
+    — Result: V_post sub-threshold.
+              Mg block partially remains.
+              NMDA gate opens partially or not at all.
+              This is the most common state during low-rate firing
+              without a coincident bAP.
 
-#### **Metabolic-Recovery**
+  Vpost_Passive: Episode
+    — g_AMPA empty AND V_bAP empty
+    — Result: V_post at rest.
+              Mg block fully intact.
+              No Ca_post entry possible.
+              Na/K-ATPase cost minimal.
 
-- **Astrocyte_Supply_Active: Episode**
-  - — `Glucose_level` full; `ATP_level_post` is replenished.
-- **Astrocyte_Supply_Crises: Episode**
-  - — `Glucose_level` low; `ATP_level_post` remains empty; Ca2+ pumps fail.
+  Desensitization-Context: Context
+    Modulates g_AMPA independently of NT_cleft.
+    Sustained NT exposure drives receptors into a closed state
+    that persists even when NT remains present.
 
-#### **Structural-Update**
+    DesensitizationRising: Episode
+      — NT_cleft sustained high (multiple consecutive ms)
+      — Desensitization rises each ms
+      — g_AMPA effectively reduced despite NT presence
+      — attenuates Vpost_Maximum toward Vpost_Attenuated
 
-- **AMPA_Population_Increase: Episode**
-  - — Triggered by `Plasticity_LTP` AND `ATP_level_post` NOT empty.
-  - — Result: `g_AMPA_baseline` shifts higher for next cycle.
-- **AMPA_Population_Decrease: Episode**
-  - — Triggered by `Plasticity_LTD`.
-  - — Result: `g_AMPA_baseline` shifts lower.
+    DesensitizationRecovering: Episode
+      — NT_cleft low or empty
+      — Desensitization decays with tau_desensitization = 500 ms
+      — g_AMPA ceiling restored gradually
 
----
+NMDA-Coincidence: Context
+  Strict AND gate: both NT (ligand) and V_post (voltage) must
+  be simultaneously non-zero for Ca_post to rise.
+  Unlike presynaptic VGCCs which open with any spike, NMDA
+  requires coincidence. This makes Ca_post a detector of
+  coordinated pre+post activity, not just input rate.
 
-### **Key Structural Observations**
+  NMDA_Open: Episode
+    — NT_cleft full AND V_post maximum (Vpost_Maximum active)
+    — Mg block fully lifted
+    — Ca_post surges — LTP territory
+    — ATP_demand_post rises sharply (PMCA must clear Ca_post)
+    — if sustained → Ca_post_history crosses eCB threshold
 
-1. **The Vpost Priority:** Vpost​ is now the "sum" of local input and global feedback. This allows the model to simulate both **Hebbian learning** (needs a bAP) and **Homeostatic Scaling** (where enough local AMPA activity can eventually trigger the NMDA gate alone).
-2. **The ATP Bottleneck for LTP:** Note that in the `min` behaviors, I’ve added a constraint: LTP requires `ATP_level_post` to be healthy. Moving receptors into the membrane is a physical "work" process. If the synapse is energy-starved, it might "decide" to do LTP in the `sec` loop but fail to **execute** it in the `min` loop.
-3. **The Coincidence Hierarchy:**
-   - **LTP** = Perfect Timing (NT + bAP).
-   - **LTD** = Misaligned Timing (Low NT or Out-of-sync bAP).
-   - **False eCB** = Metabolic Failure (No NT, No bAP, just Low ATP).
+  NMDA_LogicBlocked: Episode
+    — NT_cleft full BUT V_post attenuated or passive
+    — Mg block partially or fully intact
+    — Ca_post does not rise despite NT presence
+    — Result: presynapse fired but postsynapse was not ready
+              No plasticity signal generated
+              This is the mechanism for input selectivity:
+              only synapses active during postsynaptic firing
+              produce a Ca_post signal
+
+  NMDA_LigandBlocked: Episode
+    — V_post maximum BUT NT_cleft empty
+    — No glutamate to open the channel
+    — Ca_post entry zero despite full depolarisation
+    — Result: bAP arrived but presynapse was silent
+              Again no plasticity signal
+              The AND logic enforces true coincidence
+
+Ca-Dynamics-Context: Context
+  Ca_post clearance rate depends entirely on ATP_level_post.
+  This is the bridge from the ATP loop into the Ca2+ loop.
+  When ATP fails, Ca_post clearance fails, and the Ca2+ loop
+  becomes corrupted — Ca_post reflects pump state rather
+  than genuine coincidence events.
+
+  Clearance_Optimal: Episode
+    — ATP_level_post full → pump_scale_post near 1
+    — PMCA (ATP-gated) + NCX (always on) both clearing
+    — Ca_post returns to baseline between events
+    — Each coincidence event is temporally isolated
+    — ATP_demand_post increases proportionally to Ca_post load
+
+  Clearance_Reduced: Episode
+    — ATP_level_post medium → pump_scale_post reduced
+    — Ca_post clears more slowly
+    — Residual elevation begins accumulating between events
+    — Ca_post_history starts drifting upward
+    — eCB threshold may be approached during heavy firing
+
+  Clearance_Failing: Episode
+    — ATP_level_post low or empty → pump_scale_post near 0
+    — Only NCX clearing (floor, not rescue)
+    — Ca_post accumulates regardless of coincidence activity
+    — False Trigger conditions: Ca_post_history crosses eCB
+      threshold without genuine NMDA overactivity
+    — Excitotoxicity risk if Ca_post elevation is sustained
+
+━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━
+sec: behaviors — Signal Integration and Fate
+━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━
+
+Synaptic-Weight-Decision: Context
+  Ca_post_history (2 s rolling mean of Ca_post) determines
+  the plasticity signal. The threshold logic is graded:
+  the same variable produces opposite outcomes depending
+  on whether it is above or below the LTP/LTD boundary.
+  ATP_level_post gates LTP expression but not LTD —
+  strengthening requires energy, weakening does not.
+
+  Plasticity_LTP: Episode
+    — Ca_post_history full (above Ca_post_LTP threshold)
+    — High-frequency or high-amplitude coincidence detected
+    — Tags synapse for AMPA receptor insertion
+    — Requires ATP_level_post NOT empty for expression
+      (CaMKII phosphorylation and receptor trafficking are
+       ATP-dependent — energy failure blocks LTP even if
+       the Ca_post signal is correct)
+    — [GAP] LTP expression writes g_AMPA_baseline upward
+             in the minutes loop
+
+  Plasticity_Boundary: Episode
+    — Ca_post_history medium
+    — Poorly timed or low-frequency coincidence
+    — Neither LTP nor LTD threshold crossed
+    — Synapse weight unchanged this cycle
+
+  Plasticity_LTD: Episode
+    — Ca_post_history low but non-zero
+    — Weak or mistimed coincidence — presynapse fired
+      but postsynapse was not sufficiently depolarised
+    — Tags synapse for AMPA receptor removal
+    — Less ATP-dependent than LTP; can proceed under
+      mild energy stress
+    — [GAP] LTD expression writes g_AMPA_baseline downward
+             in the minutes loop
+
+  Plasticity_Silent: Episode
+    — Ca_post_history empty (prolonged absence of activity)
+    — Homeostatic depression: unused synapses weaken
+    — [GAP] not yet modelled; would require Ca_post_trace
+             integration over hours
+
+Retrograde-Feedback: Context
+  eCB synthesis is triggered by Ca_post_history, not V_post.
+  It is Ca2+ in the spine — not voltage — that activates the
+  enzymes (DAGL, PLC) that produce endocannabinoids.
+  The model cannot distinguish internally between the two
+  causes of elevated Ca_post_history (genuine vs pump failure)
+  but the consequences differ: one is communication,
+  the other is survival.
+
+  eCB_Synthesis_Active: Episode
+    — Ca_post_history > eCB_threshold (0.7)
+
+    — Logic A (Genuine Protection):
+        Cause   : sustained NMDA_Open events — real overactivity
+        Effect  : appropriate retrograde stop signal
+        Outcome : presynapse reduces NT → NT_cleft falls →
+                  NMDA closes → Ca_post load drops →
+                  Ca_post_history falls → eCB synthesis subsides
+                  Loop closes correctly
+
+    — Logic B (False Trigger — Excitotoxic Protection):
+        Cause   : Clearance_Failing — Ca_post elevated by
+                  pump failure, not genuine coincidence
+        Effect  : presynapse silenced without real overactivity
+        Outcome : NT_cleft falls → NMDA closes → Ca_post
+                  load drops → ATP_demand_post falls →
+                  ATP_level_post recovers → pumps restart →
+                  Ca_post clears → Ca_post_history falls →
+                  eCB synthesis subsides
+                  Desperate survival loop — buys time for
+                  metabolic recovery
+
+  eCB_Synthesis_Idle: Episode
+    — Ca_post_history < eCB_threshold
+    — eCB_level decays with tau_eCB_decay = 10000 ms
+    — Presynaptic suppression lifts gradually
+    — 10 s decay means suppression outlasts the trigger —
+      prevents immediate re-engagement before Ca_post
+      has stabilised
+
+━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━
+min: behaviors — Bioenergetics and Structural Change
+━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━
+
+Metabolic-Recovery: Context
+  ATP_level_post is computed from Glucose_level (shared
+  supply) minus ATP_demand_post (postsynaptic-specific cost).
+  The shared supply creates the coupling: both pre and post
+  deplete the same astrocyte glucose budget simultaneously.
+  Presynaptic silence is therefore metabolically beneficial
+  to the postsynapse — less NT means less NMDA activation
+  means less Ca_post means less PMCA cost.
+
+  Astrocyte_Supply_Active: Episode
+    — Glucose_level full
+    — ATP_demand_post within supply capacity
+    — ATP_level_post replenished each cycle
+    — All three loops operating normally
+
+  Astrocyte_Supply_Stressed: Episode
+    — Glucose_level medium OR ATP_demand_post elevated
+    — ATP_level_post partially reduced
+    — Clearance_Reduced begins
+    — Plasticity_LTP at risk (ATP dependency)
+
+  Astrocyte_Supply_Crisis: Episode
+    — Glucose_level low OR ATP_demand_post chronically high
+    — ATP_level_post near empty
+    — Clearance_Failing — only NCX clearing Ca_post
+    — False Trigger likely → eCB_Synthesis_Active (Logic B)
+    — Presynaptic silence indirectly reduces postsynaptic
+      ATP demand — the coupled protection mechanism
+
+Structural-Update: Context
+  Long-term changes to AMPA receptor density.
+  These are the physical substrate of learning and memory.
+  [GAP] g_AMPA_baseline not yet implemented in the model.
+  Would be written in Loop 3 and read by Loop 1 as the
+  ceiling of receptor_conductance.
+
+  AMPA_Population_Increase: Episode
+    — Triggered by Plasticity_LTP
+    — AND ATP_level_post NOT empty
+    — g_AMPA_baseline shifts higher for next cycle
+    — More AMPA receptors → stronger Vpost_Maximum
+    — Easier to reach NMDA_Open in future events
+    — Positive feedback: LTP makes future LTP more likely
+
+  AMPA_Population_Decrease: Episode
+    — Triggered by Plasticity_LTD or Plasticity_Silent
+    — g_AMPA_baseline shifts lower
+    — Fewer AMPA receptors → Vpost_Attenuated more common
+    — Harder to reach NMDA_Open → weakens synapse further
+    — Negative feedback: LTD stabilises by reducing
+      future coincidence probability
+```