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Update 2026-06-06-tripartite_synapse_v2.md

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ocrampal
2026-06-07 11:23:27 +02:00
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elements/astrocyte/appunti/2026-06-06-tripartite_synapse_v2.md
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@@ -314,15 +314,15 @@ VAR astro_structure // synaptic environment: perisynaptic distance + ECM integr
---
---
# SCOPE: DAY
## SCOPE: DAY
Behaviors run. Budgets are consumed. Traces are deposited.
Structural variables are READ only — never written.
---
## PRE — Presynaptic Bouton
### PRE — Presynaptic Bouton
### CONTEXT: AP
#### CONTEXT: AP
```
scope DAY | context AP:
@@ -352,7 +352,7 @@ scope DAY | context AP:
pre_budget += astro_lactate × pre_fraction
```
### CONTEXT: NOT_AP
#### CONTEXT: NOT_AP
```
scope DAY | context NOT_AP:
@@ -374,9 +374,9 @@ scope DAY | context NOT_AP:
---
## POST — Dendritic Spine
### POST — Dendritic Spine
### CONTEXT: NOT_bAP
#### CONTEXT: NOT_bAP
```
scope DAY | context NOT_bAP:
@@ -403,7 +403,7 @@ scope DAY | context NOT_bAP:
post_trace *= PKA_amplifier // (covers: GluA1_Ser845_primed → lower insertion threshold)
```
### CONTEXT: bAP
#### CONTEXT: bAP
```
scope DAY | context bAP:
@@ -422,9 +422,9 @@ scope DAY | context bAP:
---
## DEND — Dendritic Branch
### DEND — Dendritic Branch
### CONTEXT: CONTINUOUS
#### CONTEXT: CONTINUOUS
```
scope DAY | context CONTINUOUS:
@@ -459,9 +459,9 @@ scope DAY | context CONTINUOUS:
---
## SOMA — Cell Body
### SOMA — Cell Body
### CONTEXT: AP
#### CONTEXT: AP
```
scope DAY | context AP:
@@ -482,7 +482,7 @@ scope DAY | context AP:
soma_budget -= AP_generation_cost // (covers: AP ionic currents + Na/K reset)
```
### CONTEXT: NOT_AP
#### CONTEXT: NOT_AP
```
scope DAY | context NOT_AP:
@@ -507,9 +507,9 @@ scope DAY | context NOT_AP:
---
## ASTRO — Astrocyte
### ASTRO — Astrocyte
### CONTEXT: CONTINUOUS
#### CONTEXT: CONTINUOUS
```
scope DAY | context CONTINUOUS:
@@ -538,7 +538,7 @@ scope DAY | context CONTINUOUS:
---
## Special Case — Shockwave Lockdown (any scope)
### Special Case — Shockwave Lockdown (any scope)
```
scope DAY or NIGHT | context OVERLOAD:
@@ -556,12 +556,12 @@ scope DAY or NIGHT | context OVERLOAD:
---
---
# SCOPE: NIGHT
## SCOPE: NIGHT
Structural variables WRITTEN. Budgets replenished. Traces evaluated and cleared.
---
## Step 1 — Replenish All Budgets
### Step 1 — Replenish All Budgets
```
scope NIGHT | step 1:
@@ -585,7 +585,7 @@ scope NIGHT | step 1:
---
## Step 2 — Structural Commit for Each Tagged Compartment
### Step 2 — Structural Commit for Each Tagged Compartment
```
scope NIGHT | step 2:
@@ -644,7 +644,7 @@ scope NIGHT | step 2:
---
## Step 3 — Homeostatic Scaling
### Step 3 — Homeostatic Scaling
```
scope NIGHT | step 3:
@@ -664,7 +664,7 @@ scope NIGHT | step 3:
---
## Step 4 — Clear All DAY Traces
### Step 4 — Clear All DAY Traces
```
scope NIGHT | step 4:
@@ -682,7 +682,7 @@ scope NIGHT | step 4:
---
## Key Asymmetry — Structural Variables Amplify Both Directions
### Key Asymmetry — Structural Variables Amplify Both Directions
```
// astro_structure controls diffusion geometry and D-serine tonic level simultaneously: