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Update 2026-06-06-tripartite_synapse_v2.md

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ocrampal
2026-06-07 11:23:27 +02:00
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elements/astrocyte/appunti/2026-06-06-tripartite_synapse_v2.md
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@@ -314,15 +314,15 @@ VAR astro_structure // synaptic environment: perisynaptic distance + ECM integr
--- ---
--- ---
# SCOPE: DAY ## SCOPE: DAY
Behaviors run. Budgets are consumed. Traces are deposited. Behaviors run. Budgets are consumed. Traces are deposited.
Structural variables are READ only — never written. Structural variables are READ only — never written.
--- ---
## PRE — Presynaptic Bouton ### PRE — Presynaptic Bouton
### CONTEXT: AP #### CONTEXT: AP
``` ```
scope DAY | context AP: scope DAY | context AP:
@@ -352,7 +352,7 @@ scope DAY | context AP:
pre_budget += astro_lactate × pre_fraction pre_budget += astro_lactate × pre_fraction
``` ```
### CONTEXT: NOT_AP #### CONTEXT: NOT_AP
``` ```
scope DAY | context NOT_AP: scope DAY | context NOT_AP:
@@ -374,9 +374,9 @@ scope DAY | context NOT_AP:
--- ---
## POST — Dendritic Spine ### POST — Dendritic Spine
### CONTEXT: NOT_bAP #### CONTEXT: NOT_bAP
``` ```
scope DAY | context NOT_bAP: scope DAY | context NOT_bAP:
@@ -403,7 +403,7 @@ scope DAY | context NOT_bAP:
post_trace *= PKA_amplifier // (covers: GluA1_Ser845_primed → lower insertion threshold) post_trace *= PKA_amplifier // (covers: GluA1_Ser845_primed → lower insertion threshold)
``` ```
### CONTEXT: bAP #### CONTEXT: bAP
``` ```
scope DAY | context bAP: scope DAY | context bAP:
@@ -422,9 +422,9 @@ scope DAY | context bAP:
--- ---
## DEND — Dendritic Branch ### DEND — Dendritic Branch
### CONTEXT: CONTINUOUS #### CONTEXT: CONTINUOUS
``` ```
scope DAY | context CONTINUOUS: scope DAY | context CONTINUOUS:
@@ -459,9 +459,9 @@ scope DAY | context CONTINUOUS:
--- ---
## SOMA — Cell Body ### SOMA — Cell Body
### CONTEXT: AP #### CONTEXT: AP
``` ```
scope DAY | context AP: scope DAY | context AP:
@@ -482,7 +482,7 @@ scope DAY | context AP:
soma_budget -= AP_generation_cost // (covers: AP ionic currents + Na/K reset) soma_budget -= AP_generation_cost // (covers: AP ionic currents + Na/K reset)
``` ```
### CONTEXT: NOT_AP #### CONTEXT: NOT_AP
``` ```
scope DAY | context NOT_AP: scope DAY | context NOT_AP:
@@ -507,9 +507,9 @@ scope DAY | context NOT_AP:
--- ---
## ASTRO — Astrocyte ### ASTRO — Astrocyte
### CONTEXT: CONTINUOUS #### CONTEXT: CONTINUOUS
``` ```
scope DAY | context CONTINUOUS: scope DAY | context CONTINUOUS:
@@ -538,7 +538,7 @@ scope DAY | context CONTINUOUS:
--- ---
## Special Case — Shockwave Lockdown (any scope) ### Special Case — Shockwave Lockdown (any scope)
``` ```
scope DAY or NIGHT | context OVERLOAD: scope DAY or NIGHT | context OVERLOAD:
@@ -556,12 +556,12 @@ scope DAY or NIGHT | context OVERLOAD:
--- ---
--- ---
# SCOPE: NIGHT ## SCOPE: NIGHT
Structural variables WRITTEN. Budgets replenished. Traces evaluated and cleared. Structural variables WRITTEN. Budgets replenished. Traces evaluated and cleared.
--- ---
## Step 1 — Replenish All Budgets ### Step 1 — Replenish All Budgets
``` ```
scope NIGHT | step 1: scope NIGHT | step 1:
@@ -585,7 +585,7 @@ scope NIGHT | step 1:
--- ---
## Step 2 — Structural Commit for Each Tagged Compartment ### Step 2 — Structural Commit for Each Tagged Compartment
``` ```
scope NIGHT | step 2: scope NIGHT | step 2:
@@ -644,7 +644,7 @@ scope NIGHT | step 2:
--- ---
## Step 3 — Homeostatic Scaling ### Step 3 — Homeostatic Scaling
``` ```
scope NIGHT | step 3: scope NIGHT | step 3:
@@ -664,7 +664,7 @@ scope NIGHT | step 3:
--- ---
## Step 4 — Clear All DAY Traces ### Step 4 — Clear All DAY Traces
``` ```
scope NIGHT | step 4: scope NIGHT | step 4:
@@ -682,7 +682,7 @@ scope NIGHT | step 4:
--- ---
## Key Asymmetry — Structural Variables Amplify Both Directions ### Key Asymmetry — Structural Variables Amplify Both Directions
``` ```
// astro_structure controls diffusion geometry and D-serine tonic level simultaneously: // astro_structure controls diffusion geometry and D-serine tonic level simultaneously: