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- **Ca2+**: Calcium Ion entering the Presynapse when VCGG open. They are key to check the concentration, release vescicles and modulation - **Ca2+**: Calcium Ion entering the Presynapse when VCGG open. They are key to check the concentration, release vescicles and modulation
- **Ca2Micro**: free cytosolic Ca2+ in microdomain that influence NT release. Normally returns to ~0 between spikes; stays elevated when pumps fail - **Ca2Micro**: free cytosolic Ca2+ in microdomain that influence NT release. Normally returns to ~0 between spikes; stays elevated when pumps fail
- **ReadyReleasablePool**: Readily Releasable Pool: The Readily Releasable Pool consists of the vesicles that are "docked" and "primed" at the active zone of the synapse. - **Rrp**: Readily Releasable Pool: The Readily Releasable Pool consists of the vesicles that are "docked" and "primed" at the active zone of the synapse.
-- Location: Directly touching the presynaptic membrane. -- Location: Directly touching the presynaptic membrane.
-- Function: These are the first to be released when an action potential arrives. -- Function: These are the first to be released when an action potential arrives.
-- Characteristics: This pool is very small (usually only about 0.5% to 5% of total vesicles) and can be exhausted quickly during high-frequency firing, leading to "short-term depression" of the signal. -- Characteristics: This pool is very small (usually only about 0.5% to 5% of total vesicles) and can be exhausted quickly during high-frequency firing, leading to "short-term depression" of the signal.
@@ -110,7 +110,6 @@ container: BEH-AXO
-- Characteristics: This makes up the vast majority of the vesicles (up to 80% or 90%). -- Characteristics: This makes up the vast majority of the vesicles (up to 80% or 90%).
- **Nt**: Neuro Transmitter, released in the synapse by the vescicles - **Nt**: Neuro Transmitter, released in the synapse by the vescicles
- **CaTraces**: sono le tracce di permanenza della concentrazione di Ca2+. Servono alla modulazione (TUN) - **CaTraces**: sono le tracce di permanenza della concentrazione di Ca2+. Servono alla modulazione (TUN)
- **TagRelease**: forse non serve, ma indica il rilascio di NT da parte di una Pre.
```Gen ```Gen
container: BEH-PRE container: BEH-PRE