From 65cfd8476c8a1d5cee3a8f9b578b8d3e2f5b7dc3 Mon Sep 17 00:00:00 2001 From: Sergio Marchetti Date: Sat, 16 May 2026 14:06:36 +0200 Subject: [PATCH] Update neuron/presynapse.md --- neuron/presynapse.md | 42 +++++++++++++++++++++++------------------- 1 file changed, 23 insertions(+), 19 deletions(-) diff --git a/neuron/presynapse.md b/neuron/presynapse.md index ef0f695..cf4b217 100644 --- a/neuron/presynapse.md +++ b/neuron/presynapse.md @@ -1,3 +1,7 @@ +--- +include_toc: true +--- + # presynapse.md Qui comprendiamo: @@ -249,7 +253,7 @@ NT empty. Qui siamo contestualizzati se Ca2+ full, il che dovrebbe significare i In tutti i casi di NT -#### NTreleaseLow: accumulator +#### NTreleaseLow: ( active: 12x ) accumulator ```Gen NTreleaseLow: ( active: 12x ) # Low type: accumulator @@ -261,7 +265,7 @@ NTreleaseLow: ( active: 12x ) # Low trace: None ``` -#### NTreleaseMedium: accumulatorv +#### NTreleaseMedium: ( active: 9x ) accumulatorv ```Gen NTreleaseMedium: ( active: 9x ) # Medium type: accumulator @@ -275,7 +279,7 @@ NTreleaseMedium: ( active: 9x ) # Medium trace: None ``` -#### NTreleaseHigh: accumulator +#### NTreleaseHigh: ( active: 3x ) accumulator ```Gen NTreleaseHigh: ( active: 3x ) # High type: accumulator @@ -301,7 +305,7 @@ Serve a: --- -#### Ca2+TracesAccumulationLow: accumulator +#### Ca2+TracesAccumulationLow: ( active: 10x ) accumulator ```Gen Ca2+TracesAccumulationLow: ( active: 10x ) type: accumulator @@ -313,7 +317,7 @@ Ca2+TracesAccumulationLow: ( active: 10x ) trace: None ``` -#### Ca2+TracesAccumulationMedium: accumulator +#### Ca2+TracesAccumulationMedium: ( active: 6x ) accumulator ```Gen Ca2+TracesAccumulationMedium: ( active: 6x ) # medium type: accumulator @@ -325,7 +329,7 @@ Ca2+TracesAccumulationMedium: ( active: 6x ) # medium trace: None ``` -#### Ca2+TracesAccumulationHigh: accumulator +#### Ca2+TracesAccumulationHigh: ( active: 10x ) accumulator ```Gen Ca2+TracesAccumulationHigh: ( active: 10x ) # high type: accumulator @@ -345,7 +349,7 @@ eCB dipende da POST. Tende a modulare l'entrata di Ca2+ degli VGCC. Qui non facciamo un flush di eCB, riduciamo ogni mezzo secondo (context) di un RF di questo episodio. -#### eCBClearance: accumulator +#### eCBClearance: ( active: 24x ) accumulator ```Gen eCBClearance: ( active: 24x ) # Slow type: accumulator @@ -357,7 +361,7 @@ eCBClearance: ( active: 24x ) # Slow trace: None ``` -#### RPShuttleLow: accumulator +#### RPShuttleLow: ( active: 48x ) accumulator This happens in the seconds loop, once per second. @@ -378,7 +382,7 @@ RPShuttleLow: ( active: 48x ) # Low trace: None ``` -#### RPShuttleMedium: accumulator +#### RPShuttleMedium: ( active: 24x ) accumulator The "Sub-Optimal" State. The machinery is working, but it's held back by partial limitations. This covers cases where the signal is steady but the "piston" isn't firing at full speed, or where a high vacancy in the RRP (emptiness) forces a low signal to work a bit harder. @@ -398,7 +402,7 @@ RPShuttleMedium: ( active: 24x ) # Medium trace: None ``` -#### RPShuttleHigh: accumulator +#### RPShuttleHigh: ( active: 12x ) accumulator The "High Performance" State. Multiple systems are optimized, but one is still at a "mediumness" level. This represents an active synapse that hasn't reached its absolute peak because either the supply is only 50% or the RRP isn't empty enough to create that "maximal vacuum" pull. @@ -449,7 +453,7 @@ Each tier buys time for the one below it to respond. When all three are depleted ### TunPossible_ctx: PRESYNAPSE -#### Ca2+TracesClearance: accumulator +#### Ca2+TracesClearance: ( active: 30x ) accumulator Qui facciamo un flush di CaTraceX. Deve essere fatto a valle del tuning. @@ -510,7 +514,7 @@ Qui semplifichiamo: Devo controllare che le condizioni sotto siano esaustive. Qui ho confuso high con low, e inoltre ho messo NT per mGluR che devo controllare che abbia senso. -#### Ca2+enterLow: accumulator +#### Ca2+enterLow: ( active: 12x ) accumulator ```Gen Ca2+enterLow: ( active: 12x ) # Low type: accumulator @@ -522,7 +526,7 @@ Ca2+enterLow: ( active: 12x ) # Low trace: None ``` -#### Ca2+enterMedium: accumulator +#### Ca2+enterMedium: ( active: 6x ) accumulator ```Gen Ca2+enterMedium: ( active: 6x ) # Medium type: accumulator @@ -536,7 +540,7 @@ Ca2+enterMedium: ( active: 6x ) # Medium trace: None ``` -#### Ca2+enterHigh: accumulator +#### Ca2+enterHigh: ( active: 3x ) accumulator ```Gen Ca2+enterHigh: ( active: 3x ) # High type: accumulator @@ -563,7 +567,7 @@ Qui disinguiamo: - NOT ca2+ fullness che svuota piu' lentamente - da capire se serve veramente questa distinzione per il tempo di svuotamento. -#### Ca2+ClearanceLow: accumulator +#### Ca2+ClearanceLow: ( active: 24x ) accumulator ```Gen Ca2+ClearanceLow: ( active: 24x ) # Low type: accumulator @@ -575,7 +579,7 @@ Ca2+ClearanceLow: ( active: 24x ) # Low trace: None ``` -#### Ca2+ClearanceHigh: accumulator +#### Ca2+ClearanceHigh: ( active: 4x ) accumulator ```Gen Ca2+ClearanceHigh: ( active: 4x ) # High type: accumulator @@ -607,7 +611,7 @@ VGCC-PRE-TUN tub_intricated: ``` -### TunPossible_ctx: VGCC-PRE-TUN +### TunPossible_ctx: ( active: 60x ) VGCC-PRE-TUN #### CheckVgccPreTun: contexting Qui controlliamo che ci siano le condizioni per aumentare o diminuire la quantita' di VGCC @@ -624,7 +628,7 @@ CheckVgccPreTun: ( active: 60x ) out_context: TryTunDownPreVcgg_ctx ``` -#### PossibleUpPreVgccTun: accumulator +#### PossibleUpPreVgccTun: ( active: 10x ) accumulator ```Gen PossibleUpPreVgccTun: ( active: 10x ) type: accumulator @@ -636,7 +640,7 @@ PossibleUpPreVgccTun: ( active: 10x ) trace: ``` -#### PossibleDownPreVgccTun: accumulator +#### PossibleDownPreVgccTun: ( active: 10x ) accumulator ```Gen PossibleDownPreVgccTun: ( active: 10x ) type: accumulator