varie

neuron/README.md

@@ -9,14 +9,11 @@ This framework describes a system that is not a static processor, but a living e
 ### Pillar 1: The Electrical Pillar (The Integration Layer)
 
 - Function & Reason: Pattern Extraction. The neuron acts as a spatiotemporal filter. It integrates thousands of tiny inputs across its dendritic tree (space) and within narrow windows of time. Its "output" is a declaration that a specific relevant pattern has been recognized.
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 - Timescale: Milliseconds (ms).
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 - Behaviors: Summation of Excitatory/Inhibitory Post-Synaptic Potentials (EPSPs/IPSPs), the "Tug-of-War" at the soma, and the propagation of the "Success" signal (the Spike).
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 - Elements Involved:
--- Ions: Na+ (The "Yes" current), K+ (The "No/Reset" current).
--- Hardware: Dendritic tree (The Space), VGSC/VGKC (The Timers).
+  \-- Ions: Na+ (The "Yes" current), K+ (The "No/Reset" current).
+  \-- Hardware: Dendritic tree (The Space), VGSC/VGKC (The Timers).
 
 ### Pillar 2: The Metabolic Pillar (The Constraint Layer)
 
@@ -52,16 +49,14 @@ This framework describes a system that is not a static processor, but a living e
 By combining these four pillars, the neuron becomes a Non-Static Adaptive Engine:
 
 - Selective Attention: It doesn't just pass signals; it ignores noise and only "speaks" when its specific spatial and temporal requirements are met.
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 - Self-Regulating Sensitivity: If the patterns it is expecting become too frequent or too rare, the Calcium and Structural pillars adjust the Electrical hardware to find a new "sweet spot."
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 - Metabolic Wisdom: It balances the "desire" to extract patterns against the "cost" of ATP. It is an engine that tunes itself to be as efficient as possible.
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 - Hardware-Software Unity: Unlike a computer, where the software cannot change the CPU, the neuron's "software" (the activity patterns) physically rewrites its "hardware" (the pillars) every single day.
 
 This is the portrait of a system that isn't just "running a program"—it is a biological machine constantly sculpting itself to become a better filter for the world it perceives.
 
 ---
+
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 ## Flussi e chiusure
@@ -69,15 +64,10 @@ This is the portrait of a system that isn't just "running a program"—it is a b
 ### Flusso da POST a SOMA
 
 - Gli NT che arrivano a BEH-POST-AMPA aprono i AMPA che fa entrare Na che vengono integrati nella POST
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 - Gli Na nella POST aprono NDMA che fanno entrare Ca2+
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 - Ca2+ genera VPost nel DB
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 - L'integrazione di VPost nel DB genera VDB nel SOMA
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 - L'integrazione di VDB nel SOMA determina AP
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 - Si aprono i Canali ionici del SOMA, si genera VSOMA e refractory period (emergente)
 
 ### Flusso da SOMA a POST
@@ -94,8 +84,8 @@ Based on the computational model provided, here is the complete breakdown of all
 
 ### 1. Presynaptic Behaviors
 
-* **Action Potential Arrival (`V_pre`):** When a spike occurs, the membrane potential (`V_pre_state`) jumps to a peak and decays based on `tau_V_pre`. This profile determines the duration of ion channel opening.
-* **Calcium Influx (`VGCC`):** Voltage-Gated Calcium Channels open based on `V_pre_state`. The flow is regulated by three "brakes": **eCB** (retrograde), **CDI** (inactivation), and **mGluR** (autoreceptor).
+* **Action Potential Arrival (**`V_pre`**):** When a spike occurs, the membrane potential (`V_pre_state`) jumps to a peak and decays based on `tau_V_pre`. This profile determines the duration of ion channel opening.
+* **Calcium Influx (**`VGCC`**):** Voltage-Gated Calcium Channels open based on `V_pre_state`. The flow is regulated by three "brakes": **eCB** (retrograde), **CDI** (inactivation), and **mGluR** (autoreceptor).
 * **Intracellular Buffering:** Free calcium (`Ca_micro`) is immediately captured by buffers (`B_free`). As activity increases and buffers saturate, the effective calcium concentration rises faster (**Metabolic Cascade 4**).
 * **Vesicle Release (NT):** Neurotransmitter release is **deterministic** and follows a Hill equation (simulating Synaptotagmin-1 cooperativity). It is limited by the number of vesicles in the Prontly Releasable Pool (`N_RRP`) and suppressed by high existing levels of NT in the cleft.
 * **Vesicle Recycling:** Vesicles move from the Reserve Pool (`N_RP`) to the `N_RRP` at a rate determined by the calcium trace (`Tr_Ca`). Fast recruitment occurs during high activity; slow recruitment occurs at rest.
@@ -141,7 +131,7 @@ Based on the computational model provided, here is the complete breakdown of all
 ### Logic Summary Table
 
 | Input                  | Process             | Output                              |
-| :--- | :--- | :--- |
+|------------------------|---------------------|-------------------------------------|
 | **NT in Cleft**        | AMPA / NMDA Opening | **V_post** (Postsynaptic Potential) |
 | **V_post**             | Dendritic Summation | **V_dend** (Dendritic Potential)    |
 | **V_dend**             | Somatic Integration | **V_soma** (Somatic Potential)      |