From 42bf8a2a3579a57e074668c486686389d2fa456b Mon Sep 17 00:00:00 2001 From: ocrampal Date: Thu, 4 Jun 2026 17:52:04 +0200 Subject: [PATCH] Update 2026-06-04-modulation-of-future-behavior.md --- .../appunti/2026-06-04-modulation-of-future-behavior.md | 2 ++ 1 file changed, 2 insertions(+) diff --git a/elements/astrocyte/appunti/2026-06-04-modulation-of-future-behavior.md b/elements/astrocyte/appunti/2026-06-04-modulation-of-future-behavior.md index 32d591d..faed59b 100644 --- a/elements/astrocyte/appunti/2026-06-04-modulation-of-future-behavior.md +++ b/elements/astrocyte/appunti/2026-06-04-modulation-of-future-behavior.md @@ -9,6 +9,7 @@ Together these three systems form a hierarchical filter: Ca²⁺ asks did someth ## signal state variables +```Gen // ── Ca²⁺ : event recorder ────────────────────────────────────── pre_Ca_residual // leftover Ca²⁺ between spikes — encodes recent history post_Ca_amplitude // peak rise magnitude in spine @@ -27,6 +28,7 @@ CREB_active // bool — structural gene expression enabled glutamate_spillover // extrasynaptic [glu] — only high when cleft saturated mGluR2_3_activation // presynaptic Gi — autoinhibitory brake mGluR5_activation // astrocytic Gq — IP3 → Ca²⁺ → D-serine cascade +``` ## layer 1 — Ca²⁺: did something happen?