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ocrampal
2026-05-06 11:22:08 +02:00
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commit 4283dec01a
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@@ -28,10 +28,12 @@ Downregulation:
- CB1 receptor activation (by eCBs) - CB1 receptor activation (by eCBs)
- Retrograde BDNF (brain-derived neurotrophic factor) - Retrograde BDNF (brain-derived neurotrophic factor)
> Night Time Scale
```Gen ```Gen
developer: NEURON-DEVELOPER
NEURON-DEV
type: developer # ??? (container)
contained_by: NEURON contained_by: NEURON
``` ```
@@ -40,14 +42,13 @@ developer: NEURON-DEVELOPER
```Gen ```Gen
CA2-PRESYNAPSE-DEV CA2-PRESYNAPSE-DEV
type: developer type: developer
contained_by: NEURON-DEV contained_by: NEURON-DEV
develops: NEURON/NEURON-DAY/AXON/PRESYNAPSE/tub/Ca2+ # this is the tub whose "full" must be modulated develops: NEURON/NEURON-BEH/AXON/PRESYNAPSE/tub/Ca2+
# this is the tub whose "full" must be modulated
tub_dev: tub_dev: fullMod ( fullness: 100x, active: Ca2+/full, emptiness: 50x )
- fullMod ( fullness: 100x, active: Ca2+/full, emptiness: 50x )
# qui stiamo modulando il full di Ca2+, associandolo ad # qui stiamo modulando il full di Ca2+, associandolo ad
# active di fullMod. Cambiando active di fullMod, # active di fullMod. Cambiando active di fullMod,
# si cambia la full di Ca2+ # si cambia la full di Ca2+
@@ -55,144 +56,95 @@ type: developer
tub_local: tub_local:
tub_intricated: tub_intricated:
- Nox ( contained_by: EURON/NEURON-DAY/AXON/PRESYNAPSE ) - Nox ( contained_by: NEURON/NEURON-DAY/AXON/PRESYNAPSE )
- Ecb ( contained_by: EURON/NEURON-DAY/AXON/PRESYNAPSE ) - Ecb ( contained_by: NEURON/NEURON-DAY/AXON/PRESYNAPSE )
``` ```
### CheckPreTubCa2+: Contextor ### CheckPreCa2: Contextor
***Tens Milliseconds Time Scale*** ***Tens Milliseconds Time Scale***
```Gen ```Gen
CheckPreTubCa2+: ( active: 60x ) CheckPreCa2: ( active: 60x )
type: contextor type: contextor
contained_by: NEURON-DEV contained_by: NEURON-DEV
in_context: Fixed in_context: Fixed
condition: ( empty ) condition: ( empty )
out_context: DecreaseCa2Full_ctx out_context: DecreaseCa2Full_ctx
condition: NOT ( empty ) AND NOT ( Ca2+ full ) condition: NOT ( empty ) AND NOT ( Ca2+ full ) ???
out_context: Nothing_ctx out_context: Nothing_ctx
condition: ( full) condition: ( full)
out_context: IncreaseFull_ctx out_context: IncreaseFull_ctx
``` ```
### DecreaseCa2Full: Accumulator ### DecreasePreCa2Full: Accumulator
```Gen ```Gen
DecreaseCa2Full: ( active: 1x ) DecreasePreCa2Full: ( active: 1x )
type: accumulator type: accumulator
contained_by: DEV-PRE-FULL-CA2+ contained_by: NEURON-DEV
in_context: DecreaseCa2Full_ctx in_context: DecreaseCa2Full_ctx
hypothesis: NOT ( full ) AND NOT ( empty ) hypothesis: NOT ( full ) AND NOT ( empty )
action: [ increase, decrease] action: [ increase, decrease]
trace: None trace: None
``` ```
### DEV-PRE-RRP-TUB: Developer ### IncreasePreCa2Full: Accumulator
```Gen ```Gen
developer: DEV-PRE-RRP-TUB IncreasePreCa2Full: ( active: 1x )
contained_by: DEV-TUB-FLOOR
develops: BEH-PRE/tub/Rrp # this is the tub whose "full" must be modulated type: accumulator
contained_by: NEURON-DEV
tub_dev: in_context: IncreaseCa2Full_ctx
- fullMod ( fullness: 100x, active: Rrp/fullness, emptiness: 50x ) # RrpFull "contains" a number of blocks equal to the current Full.
# qui stiamo modulando la fullness di Rrp, associandola ad hypothesis: NOT ( full ) AND NOT ( empty )
# active di fullMod. Cambiando active di fullMod, action: [ increase, decrease]
# si cambia la fullness di Rrp trace: None
```
## RRP-PRESYNAPSE-DEV: Developer
```Gen
RRP-PRESYNAPSE-DEV
type: developer
contained_by: NEURON-DEV
develops: NEURON/NEURON-BEH/AXO/PRESYNAPSE/tub/Rrp
# this is the tub whose "full" must be modulated
tub_dev: fullMod ( fullness: 100x, active: Rrp/fullness, emptiness: 50x )
# RrpFull "contains" a number of blocks equal to the current Full.
# qui stiamo modulando la fullness di Rrp, associandola ad
# active di fullMod. Cambiando active di fullMod,
# si cambia la fullness di Rrp
tub_local: tub_local:
tub_intricated: tub_intricated:
- Nox ( contained_by: BEH-POST ) - Nox ( contained_by: NEURON/NEURON-BEH/DENDRITIC-BRANCH/POSTSYNAPSE )
- Ecb ( contained_by: BEH-POST ) - Ecb ( contained_by: NEURON/NEURON-BEH/DENDRITIC-BRANCH/POSTSYNAPSE )
``` ```
#### Context1 ### Contextor
#### Episode1 ### Accumulator
## DEV-TUB-CONCEPTUAL: Developer ## PRESYNAPSE-AXO-DEV: Developer
Qui la PRE e la POST si predispongono per dare le condizioni a SYN di stabilire o eliminare una sinapsi. Per ora questo comportamento lo mettiamo in TUN perche’ non si tratta di creare o distruggere PRE o POST, ma di rendere disponibile a SYN la possibilita’ di creare o distruggere una SYN. Durante il Day c’e’ il TUN che mette a disposizione, durante il Night SYN crea o distrugge gli accoppiamenti PRE POST. Qui stiamo ragionanando sull'aggiunta o eliminazione di bottoni presynaptici. Il TUN della PRESYNAPSE e' fatto in WINNERTAKEALL/EXCITATION.
ATTENZIONE: Questo e POST e’ da cambiare, perche’ c’e’ il passaggio da TubPoss a TubPossSyn a TubAct. E’ la SYN che passa in TubAct.
> Minutes/hours Time Scale ## POSTSYNAPSE-DENDRITIC-BRANCH-DEV: Developer
```Gen Qui stiamo ragionanando sull'aggiunta o eliminazione di bottoni postsynaptici. Il TUN della POSTSYNAPSE e' fatto in WINNERTAKEALL/EXCITATION.
developer: DEV-TUB-CONCEPTUAL
contained_by: NIGHT-N
```
### AXO-PRE-TUB-DEV: Developer
Qui stiamo ragionanando sulla trasformazione fra bottone presinaptico inattivo e bottone attivo, pronto a diventare parte di una sinapsi. Il ragionamento e' locale, e mette a disposizione o toglie un bottone attivo che un altro ragionamento, in TUN-WTA, fara' su questo bottone, il bottone postisinaptico e una sinapsi disponibile. Agiamo sulla fullness di BEH-PRE.
```Gen
developer: AXO-PRE-TUB-DEV
contained_by: DEV-TUB-CONCEPTUAL
develops: N/AXO/BEH-AXO/expansion/BEH-PRE
# qui stiamo modulando fullness del tub BEH-PRE associandoli a tub_modulation prePos e PreAct.
tub_modulation:
- fulMod ( fullness: 100x, active: BEH-PRE/fullness, empty: 0x ) # aumento di possible di BEH-PRE
- actMod ( fullness: None, active: BEH-PRE/active, empty: BEH-PRE/emptiness ) # riferimento a active di BEH-PRE
context_intricated:
- TunPossible ( contained_by: TUN-N )
tub_local:
tub_intricated:
```
#### Context2
```Gen
context: CheckTunSynAxoPrePossibility
contained_by: TUN-SYN-AXO-PRE
in_context: TunPossible
rf: ( active: 60x )
condition:
out_context:
```
#### Episode2
```Gen
episode: TunSynAxoPre
contained_by: TUN-SYN-AXO-PRE
in_context: ??
rf: 1x
hypothesis: NOT () AND NOT ()
action: [ increase, decrease]
trace: None
```
### DEV-BD-BEH-POST-TUB: Developer
```Gen
developer: DEV-BD-BEH-POST-TUB
contained_by: DEV-TUB-CONCEPTUAL
...
```
#### Context3
#### Episode3