Update elements/neuron/soma.md
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@@ -11,8 +11,6 @@ Qui comprendiamo:
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- VGSC-SOMA-M: Na ion channels. Open only when VDB medium
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- VGSC-SOMA-L: Na ion channels. Open only when VDB low
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## SOMA: container
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---
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**Simplified verifiable behaviors**:
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@@ -79,16 +77,31 @@ Qui comprendiamo:
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---
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```Gen
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container: SOMA
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## SOMA: Comprehension
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expansion:
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- VGSC-SOMA-H ( full: 50x, active: 20x, empty: 10x )
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# modulated_by: VGSC-SOMA-H-TUN # possible/actual
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- VGSC-SOMA-M ( full: 50x, active: 20x, empty: 10x )
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# modulated_by: VGSC-SOMA-M-TUN # possible/actual
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- VGSC-SOMA-L ( full: 50x, active: 20x, empty: 10x )
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# modulated_by: VGSC-SOMA-L-TUN # possible/actual
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```Gen
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SOMA
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type: comprehension
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expand_comprehension:
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&VGSC-SOMA-H: VGSC-SOMA (full: 50x, active: 20x, empty: 10x)
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&VGSC-SOMA-M: VGSC-SOMA (full: 50x, active: 20x, empty: 10x)
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&VGSC-SOMA-L: VGSC-SOMA (full: 50x, active: 20x, empty: 10x)
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instantiate_container:
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SOMA-BEH []
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VGSC-SOMA-H-TUN [pass: &VGSC-SOMA-H]
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VGSC-SOMA-M-TUN [pass: &VGSC-SOMA-M]
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VGSC-SOMA-L-TUN [pass: &VGSC-SOMA-L]
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```
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### SOMA-BEH: Container
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```Gen
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SOMA-BEH
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type: container
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activity_scope: !DAY
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tub_local:
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- VDB
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@@ -99,10 +112,9 @@ container: SOMA
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tub_intricated:
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- SpikeTrainTraces ( contained_in: DAY-N )
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```
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#### any
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### ms: SOMA
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#### SOMA-Status: ( active: 60x ) contextor
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##### SOMA-Status: ( active: 60x ) contextor
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As dendrites deliver current (VDB), the soma acts like a capacitor. It "stores" this charge in the form of membrane potential. This contextualizes VGSC-SOMA to open ion channels that let Na+ ions in.
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@@ -111,23 +123,20 @@ This only applies if not ApCtx, or in other words, SOMA is not in refractory per
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```Gen
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SOMA-Status: ( active: 60x )
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type: contextor
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contained_by: SOMA
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contained_by: SOMA-BEH
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in_context: any
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condition: ( VDB fullness ) AND NOT AP_ctx
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out_context: VDBMax_Ctx
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condition: ( VDB mediumness ) AND NOT AP_ctx
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out_context: VDBMedium_ctx
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condition: ( VDB emptiness ) AND NOT Ap_ctx
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out_context: VDBLow_ctx
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condition: NOT ( Na empty )
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out_context: NaSpill_ctx
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```
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#### SomaSpike: ( active: 30x ) contextor
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##### SomaSpike: ( active: 30x ) contextor
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Il fatto che mettiamo il check di AP separato dal check del Soma-Status, e' perche' vogliamo poter avere un RF specifico per AP, eventualmente tunabile.
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@@ -138,7 +147,7 @@ La fullness di Na rappresenta il threshold e puo' essere modificato. La fullness
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```Gen
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SomaSpike: ( active: 30x )
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type: contextor
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contained_by: SOMA
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contained_by: SOMA-BEH
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in_context: any
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condition: ( Na fullness ) AND ( SomaRefractory emptiness )
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@@ -146,7 +155,24 @@ SomaSpike: ( active: 30x )
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out_context: bAp_ctx
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```
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#### ActiveAP: ( active: 8x ) accumulator
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#### SomaRefractorySpill: ( active: 16x ) accumulator
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Lo spill deve essere piu' lento dell'increase che avviene in ActiveAP
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```Gen
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SomaRefractorySpill: ( active: 16x )
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type: accumulator
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contained_by: SOMA-BEH
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in_context: any
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hypothesis: NOT ( SomaRefractory empty )
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action: [ decrease SomaRefractory ]
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trace:
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```
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#### Ap_ctx
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##### ActiveAP: ( active: 8x ) accumulator
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Durante la fase effettiva di spike:
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@@ -157,7 +183,7 @@ Durante la fase effettiva di spike:
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```Gen
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ActiveAP: ( active: 8x )
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type: accumulator
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contained_by: SOMA
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contained_by: SOMA-BEH
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in_context: Ap_ctx
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hypothesis: NOT Na empty
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@@ -173,14 +199,16 @@ ActiveAP: ( active: 8x )
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trace:
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```
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#### NaSpill: ( active: 8x ) accumulator
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#### NaSpill_ctx
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##### NaSpill: ( active: 8x ) accumulator
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Questo potrebbe non servire se eliminiamo tutti Na durante ActiveAP.
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```Gen
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NaSpill: ( active: 8x )
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type: accumulator
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contained_by: SOMA
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contained_by: SOMA-BEH
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in_context: NaSpill_ctx
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hypothesis: NOT ( Na emptiness )
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@@ -188,24 +216,7 @@ NaSpill: ( active: 8x )
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trace:
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```
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#### SomaRefractorySpill: ( active: 16x ) accumulator
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Lo spill deve essere piu' lento dell'increase che avviene in ActiveAP
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```Gen
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SomaRefractorySpill: ( active: 16x )
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type: accumulator
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contained_by: SOMA
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in_context: any
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hypothesis: NOT ( SomaRefractory empty )
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action: [ decrease SomaRefractory ]
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trace:
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```
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### min: SOMA
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## VGSC-SOMA-H: container
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## VGSC-SOMA: Comprehension
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Voltage Gated Sodium Channel: difficult to open (High)
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