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2026-03-08 10:01:18 +01:00
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neuron/BEH-BD.md
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# BEH-AXO.md
Qui comprendiamo:
- BEH-BD: Dendritic Branch
- BEH-POST: Postsynapsis
- BEH-POST-AMPA: AMPA receptors (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors)
# BEH-BD: Container
## BEH-BD: Container
**Dendritic Branch**: In questa prima fase, non consideriamo lo spike dendritico come comportamento. Questo limita molto il modello, perche' equipara tutte le Postsinapsi sui tre branch dendritici e non permette di fare in maniera che ad esempio due branch contestualizzino (base activity) e uno faccia scattare il threshold per lo spike somatico.
Qui BEH-DB espande solo i BEH-POST, e' un cavo di collegamento come l'assone
```Gen
Container: BEH-BD
expansion:
- BEH-POST ( fullness: 50x, active: 20x, emptiness: 10x )
# modulated_by: TUN-SYN-BD-POST possible/actual
expansion:
- BEH-POST ( fullness: 50x, active: 20x, emptiness: 10x )
# modulated_by: TUN-SYN-BD-POST possible/actual
```
## BEH-POST: Container
### BEH-POST: Container
```Gen
container: BEH-POST
expansion:
- BEH-POST-AMPA ( fullness: 10x, active: 5x, emptiness: 2x )
# modulated_by: TUN-POST-IC # possible/actual
expansion:
- BEH-POST-AMPA ( fullness: 10x, active: 5x, emptiness: 2x )
# modulated_by: TUN-POST-IC # possible/actual
tub_local:
- Ca2+ ( fullness: 60x, active: 30x, emptiness: 0x )
# modulated_by: DEV-POST-???-FULL # Full
tub_local:
- Ca2+ ( fullness: 60x, active: 30x, emptiness: 0x )
# modulated_by: DEV-POST-???-FULL # Full
- Nox ( fullness: 100x, active: 20x, emptiness: 0x ) # Nitric Oxide (NO): A gas that diffuses freely.
- Nox ( fullness: 100x, active: 20x, emptiness: 0x ) # Nitric Oxide (NO): A gas that diffuses freely.
- Ecb ( fullness: 100x, active: 20x, emptiness: 0x ) # Endocannabinoids (e.g., 2-AG)
- Ecb ( fullness: 100x, active: 20x, emptiness: 0x ) # Endocannabinoids (e.g., 2-AG)
tub_intricated:
- Nt ( contained_by: BEH-SYN )
- bAp ( contained_by: BEH-SOMA )
tub_intricated:
- Nt ( contained_by: BEH-SYN )
- bAp ( contained_by: BEH-SOMA )
```
### Context
#### Context
```Gen
context: captureNt
contained_by: BEH-POST
contained_by: BEH-POST
in_context: Fixed
rf: ( active: 10x )
in_context: Fixed
rf: ( active: 10x )
condition: (Nt full) AND NOT (bAp)
out_context: NtCaptured
condition: (Nt full) AND NOT (bAp)
out_context: NtCaptured
```
### Episode
#### Episode
### BEH-POST-AMPA: Container
## BEH-POST-AMPA: Container
```Gen
container: BEH-POST-AMPA
tub_intricated:
- Nt ( contained_by: BEH-SYN )
tub_intricated:
- Nt ( contained_by: BEH-SYN )
context_intricated:
- bAp ( contained_by: BEH-SOMA )
context_intricated:
- bAp ( contained_by: BEH-SOMA )
```
#### AmpaOpen: Episode
@@ -80,13 +84,13 @@ episode: AmpaOpen
rf: ( active: 1x )
hypothesis: NOT (Ca2+ full)
action: [Ca2+ increase]
trace: None # Se Ca+FULLNESS, lascio tracce di overflow per modulazione DOWN, da capire UP
action: [Ca2+ increase]
trace: None # Se Ca+FULLNESS, lascio tracce di overflow per modulazione DOWN, da capire UP
```
### Depolarization by bAP
Da ricordare i Dendritic VCGG che si aprono facendo entrare Ca2+ all'arrivo di bAP. In teoria abbiamo 3 Ion Channel.
Da ricordare i Dendritic VCGG che si aprono facendo entrare Ca2+ all'arrivo di bAP. In teoria abbiamo 3 Ion Channel.
- Timing: > 1 ms
- InContext: bAP backpropagating action potential
@@ -112,5 +116,3 @@ Da ricordare i Dendritic VCGG che si aprono facendo entrare Ca2+ all'arrivo di b
### Downregulation: Observable
- Downregulation: AMPA desensitization acts as low-pass filter
##