diff --git a/elements/neuron/soma.md b/elements/neuron/soma.md index b1b8ece..6b32d1c 100644 --- a/elements/neuron/soma.md +++ b/elements/neuron/soma.md @@ -19,7 +19,26 @@ SOMA _@SOMA_VGSC-M: TUB [ comprehension: SOMA_VGSC, full: 50x, active: 20x, empty: 10x ] _@SOMA_VGSC-L: TUB [ comprehension: SOMA_VGSC, full: 50x, active: 20x, empty: 10x ] - instantiation: + intrication: + + # Scope + !DAY: INTRICATION [ ref: &ORGANISM.!DAY ] + !NIGHT: INTRICATION [ ref: &ORGANISM.!NIGHT ] + + # Context + *AP: INTRICATION [ ref: &SOMA.*AP ] + *TunePossible: INTRICATION [ ref: &... ] # To be defined... + + # Tub + _SpikeTrainTraces: INTRICATION [ ref: &NEURON._SpikeTrainTraces ] + +instantiation: + + # Tub + _VDB: TUB [ full: 60x, active: 30x, empty: 0x ] + _Na: TUB [ full: 60x, active: 30x, empty: 0x ] + _Ca2: TUB [ full: 60x, active: 30x, empty: 0x ] + _SomaRefractory: TUB [ full: 60x, active: 30x, empty: 0x ] # Behaviour $: BEHAVIOUR [ behaviour: MAIN-SOMA ] @@ -31,31 +50,25 @@ SOMA **Tubs:** -- **VDB**: dendrites deliver current +- **_VDB**: dendrites deliver current -- **Na**: are a proxy for the Coulombs of charge building up on the somatic membrane. They are used to check threshold, but also to mimic Na+ and K+ pumping +- **_Na**: are a proxy for the Coulombs of charge building up on the somatic membrane. They are used to check threshold, but also to mimic Na+ and K+ pumping -- **Ca2+**: Medium term traces to guide tuning and Night development. It is a local trace, ATP is a global (Astrocyte) +- **_Ca2**: Medium term traces to guide tuning and Night development. It is a local trace, ATP is a global (Astrocyte) -- **SpikeTrainTraces**: sono le tracce che consentono al neurone di far partire il Tuning neuronale, quando e' lontano da uno spike-train, ovvero e' in riposo. +- **_SpikeTrainTraces**: sono le tracce che consentono al neurone di far partire il Tuning neuronale, quando e' lontano da uno spike-train, ovvero e' in riposo. -- **SomaRefractory**: tracce di refractory +- **_SomaRefractory**: tracce di refractory ### MAIN-SOMA: Container ```Gen MAIN-SOMA - type: container - activity_scope: !DAY + type: behaviour + + within_scope: !DAY - tub_local: - - VDB - - Na - - Ca2+ - - SomaRefractory - tub_intricated: - - SpikeTrainTraces ( contained_in: DAY-N ) ``` #### any @@ -123,7 +136,7 @@ Durante la fase effettiva di spike: - eliminiamo Na accumulati. Qui ad un RF molto maggiore che con NaSpill. In teoria qui dovremmo eliminare tutti gli Na e NaSpill potrebbe non servire. - riempiamo SomaRefractory per fase di refractory -- riempiamo Ca2+ per le tracce medio termine di potenziamento/depotenziamento. +- riempiamo _Ca2 per le tracce medio termine di potenziamento/depotenziamento. ```Gen ActiveAP: ( active: 8x ) @@ -139,8 +152,8 @@ ActiveAP: ( active: 8x ) action: [ increase SomaRefractory ] trace: - hypothesis: NOT Ca2+ full - action: [ increase Ca2+ ] + hypothesis: NOT _Ca2 full + action: [ increase _Ca2 ] trace: ```