Update elements/neuron/soma.md
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@@ -8,16 +8,14 @@ include_toc: true
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Expansions and modulations:
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- is expanded by: [NEURON](neuron.md)
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- expands: SOMA_VGSC
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- expands: VGCC_SOMA
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```Gen
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SOMA
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type: comprehension
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expansion:
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_@SOMA_VGSC-H: TUB [ comprehension: SOMA_VGSC, full: 50x, active: 20x, empty: 10x ]
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_@SOMA_VGSC-M: TUB [ comprehension: SOMA_VGSC, full: 50x, active: 20x, empty: 10x ]
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_@SOMA_VGSC-L: TUB [ comprehension: SOMA_VGSC, full: 50x, active: 20x, empty: 10x ]
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_@VGCC_SOMA: TUB [ comprehension: VGCC_SOMA, full: 50x, active: 20x, empty: 10x ]
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intrication:
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@@ -46,10 +44,7 @@ instantiation:
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# Behaviour
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$: BEHAVIOUR [ behaviour: MAIN-SOMA ]
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$: BEHAVIOUR [ behaviour: SOMA_VGSC_H_TUN ]
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SOMA_VGSC_M_TUN [pass: &SOMA_VGSC_M]
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SOMA_VGSC_L_TUN [pass: &SOMA_VGSC_L]
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$: BEHAVIOUR [ behaviour: VGCC_SOMA_TUN ]
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```
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**Tubs:**
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@@ -80,7 +75,7 @@ MAIN-SOMA
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##### SOMA-Status: ( active: 60x ) contextor
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As dendrites deliver current (VDB), the soma acts like a capacitor. It "stores" this charge in the form of membrane potential. This contextualizes SOMA_VGSC to open ion channels that let Na+ ions in.
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As dendrites deliver current (VDB), the soma acts like a capacitor. It "stores" this charge in the form of membrane potential. This contextualizes VGCC_SOMA to open ion channels that let Na+ ions in.
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This only applies if not ApCtx, or in other words, SOMA is not in refractory period.
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@@ -170,24 +165,60 @@ ActiveAP
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```
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## SOMA_VGSC: Comprehension
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## VGCC_SOMA
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Voltage Gated Sodium Channel: difficult to open (High)
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```Gen
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container: SOMA_VGSC-H
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VGCC_SOMA
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type: comprehension
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tub_local:
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VGSCRefractoryH ( full: 60x, active: 30x, empty: 0x )
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expansion:
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tub_intricated:
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Na ( contained_in: SOMA)
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intrication:
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context_intricated:
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VDBMaxCtx ( contained_by: SOMA )
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# Scope
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!DAY: INTRICATION [ ref: &ORGANISM.!DAY ]
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!NIGHT: INTRICATION [ ref: &ORGANISM.!NIGHT ]
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# Context
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# Tub
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_Na: INTRICATION [ ref: &SOMA._Na ]
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instantiation:
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# Context
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*VDBMaxCtx: CONTEXT []
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*VDBMediumCtx: CONTEXT []
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*VDBMLowCtx: CONTEXT []
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# Tub
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_VGSCRefractoryH: TUB [ full: 60x, active: 30x, empty: 0x )
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_VGSCRefractoryM: TUB [ full: 60x, active: 30x, empty: 0x )
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_VGSCRefractoryL: TUB [ full: 60x, active: 30x, empty: 0x )
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# Behaviour
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$: BEHAVIOUR [ behaviour: VGCC_SOMA_BEH_H]
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$: BEHAVIOUR [ behaviour: VGCC_SOMA_BEH_M]
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$: BEHAVIOUR [ behaviour: VGCC_SOMA_BEH_L]
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```
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### VGCC_SOMA_BEH_H: !DAY
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```Gen
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VGCC_SOMA_BEH_H
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type: behaviour
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within_scope: !DAY
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snippets:
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@: CONTEXTOR [ snippet: VGSC-H_Status, rf: active 60x ]
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@: ACCUMULATOR [ snippet: NaEnterH, rf: active 1x ]
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@: ACCUMULATOR [ snippet: VGSCRefractoryHSpill, rf: active 1x ]
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```
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### sec: SOMA_VGSC-H
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### sec: VGCC_SOMA-H
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#### VGSC-H_Status: ( active: 60x ) contextor
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@@ -196,7 +227,6 @@ Il check su refractory deve essere fatto ad un RF maggiore della eliminazione di
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```Gen
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VGSC-H_Status: ( active: 60x )
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type: contextor
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contained_by: SOMA_VGSC-H
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in_context: any
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condition: VDBMaxCtx AND ( VGSCRefractoryH emptiness )
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@@ -214,7 +244,7 @@ Questo sopra è il commmento della versione precedente, ora la quantità di NA i
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```Gen
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NaEnterH: ( active: 1x )
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type: accumulator
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contained_by: SOMA_VGSC-H
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contained_by: VGCC_SOMA-H
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in_context: NaEnterH_ctx
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hypothesis: ( NOT Na full )
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@@ -233,7 +263,7 @@ Lo Spill deve avere un rf maggiore dell'interacting che incrementa VGSCRefractor
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```Gen
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VGSCRefractoryHSpill: ( active: 1x )
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type: accumulator
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contained_by: SOMA_VGSC-H
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contained_by: VGCC_SOMA-H
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in_context: VGSCRefractoryHSpill_ctx
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hypothesis: NOT ( VGSCRefractoryH empty )
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@@ -241,12 +271,14 @@ VGSCRefractoryHSpill: ( active: 1x )
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trace: None
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```
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## SOMA_VGSC-M: container
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## VGCC_SOMA-M: container
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Voltage Gated Sodium Channel: less difficult to open (Medium)
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```Gen
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container: SOMA_VGSC-M
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container: VGCC_SOMA-M
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tub_local:
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VGSCRefractoryM ( full: 60x, active: 30x, empty: 0x )
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@@ -258,7 +290,7 @@ container: SOMA_VGSC-M
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VDBMedCtx ( contained_by: SOMA )
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```
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### sec: SOMA_VGSC-M
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### sec: VGCC_SOMA-M
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#### VGSC-M_TPC: ( active: 60x ) contextor
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@@ -267,7 +299,7 @@ Il check su refractory deve essere fatto ad un RF maggiore della eliminazione di
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```Gen
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VGSC-M_Status: ( active: 60x )
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type: contextor
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contained_by: SOMA_VGSC-M
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contained_by: VGCC_SOMA-M
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in_context: VDBMediumCtx OR VDBMaxCtx
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condition: ( VGSCRefractoryH emptiness )
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@@ -282,7 +314,7 @@ Questo sopra è il commmento della versione precedente, ora la quantità di NA i
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```Gen
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NaEnterM: ( active: 1x )
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type: accumulator
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contained_by: SOMA_VGSC-M
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contained_by: VGCC_SOMA-M
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in_context: NaEnterM_ctx
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hypothesis: ( NOT Na full )
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@@ -301,7 +333,7 @@ Lo Spill deve avere un rf maggiore dell'interacting che incrementa VGSCRefractor
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```Gen
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VGSCRefractoryMSpill: ( active: 1x )
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type: accumulator
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contained_by: SOMA_VGSC-M
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contained_by: VGCC_SOMA-M
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in_context: any
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hypothesis: NOT ( VGSCRefractoryM empty )
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@@ -309,12 +341,12 @@ VGSCRefractoryMSpill: ( active: 1x )
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trace: None
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```
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## SOMA_VGSC_L: container
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## VGCC_SOMA_L: container
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Voltage Gated Sodium Channel: easy to open (Low)
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```Gen
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container: SOMA_VGSC_L
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container: VGCC_SOMA_L
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tub_local:
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VGSCRefractoryL ( full: 60x, active: 30x, empty: 0x )
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@@ -326,7 +358,7 @@ container: SOMA_VGSC_L
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VDBLowCtx ( contained_by: SOMA )
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```
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### sec: SOMA_VGSC_L
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### sec: VGCC_SOMA_L
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#### VGSC-L_TPC: ( active: 60x ) contextor
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@@ -335,7 +367,7 @@ Il check su refractory deve essere fatto ad un RF maggiore della eliminazione di
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```Gen
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VGSC-L_Status: ( active: 60x )
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type: contextor
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contained_by: SOMA_VGSC_L
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contained_by: VGCC_SOMA_L
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in_context: VDBLowCtx OR VDBMediumCtx OR VDBMaxCtx
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condition: ( VGSCRefractoryH emptiness )
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@@ -350,7 +382,7 @@ Questo sopra è il commmento della versione precedente, ora la quantità di NA i
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```Gen
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NaEnterL: ( active: 1x )
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type: accumulator
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contained_by: SOMA_VGSC_L
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contained_by: VGCC_SOMA_L
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in_context: NaEnterL_ctx
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hypothesis: ( NOT Na full )
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@@ -379,14 +411,14 @@ VGSCRefractoryLSpill: ( active: 1x )
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```
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## SOMA_VGSC_TUN: Tuner
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## VGCC_SOMA_TUN: Tuner
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```Gen
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SOMA_VGSC_TUN
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VGCC_SOMA_TUN
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type: tuner
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contained_by: SOMA
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tunes: SOMA/expansion/SOMA_VGSC
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tunes: SOMA/expansion/VGCC_SOMA
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context_intricated:
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- TunPossible ( contained_by: DAY-N )
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@@ -401,7 +433,7 @@ SOMA_VGSC_TUN
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```Gen
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check_tpc: ( active: 60x )
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type: contextor
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contained_by: SOMA_VGSC-TUN
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contained_by: VGCC_SOMA-TUN
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in_context: TunPossible
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condition: ??
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